EC number:1.3.1.116

Enzyme

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     1. Oxidoreductases
        1.3 Acting on the CH-CH group of donors
            1.3.1 With NAD+ or NADP+ as acceptor
ID:1.3.1.116
Description:7-beta-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.3.1.116
BRENDA Enzyme Link: BRENDA 1.3.1.116
KEGG Enzyme Link: KEGG1.3.1.116
BioCyc Enzyme Link: BioCyc 1.3.1.116
ExPASy Enzyme Link: ExPASy1.3.1.116
EC2PDB Enzyme Link: EC2PDB 1.3.1.116
ExplorEnz Enzyme Link: ExplorEnz 1.3.1.116
PRIAM enzyme-specific profiles Link: PRIAM 1.3.1.116
IntEnz Enzyme Link: IntEnz 1.3.1.116
MEDLINE Enzyme Link: MEDLINE 1.3.1.116

EC number:1.3.1.116

MSA:

1.3.1.116;
Phylogenetic Tree:

1.3.1.116;
Uniprot:
M-CSA:
RHEA:56668 7beta-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) = 7beta-hydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[CH2;+0:4]-[*:5].[*:6]-[c;H0;+0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[n+;H0:11](-[*:12]):[cH;+0:13]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:4]-[*:5].[*:6]-[C;H0;+0:7]1=[CH;+0:13]-[N;H0;+0:11](-[*:12])-[CH;+0:10]=[CH;+0:9]-[CH2;+0:8]-1
Reaction
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References

TitleAuthorsDatePubMed ID
Characterization of the baiH gene encoding a bile acid-inducible NADH:flavin oxidoreductase from Eubacterium sp. strain VPI 12708.Franklund CV, Baron SF, Hylemon PB1993 May8491719
Expression of the bile acid-inducible NADH:flavin oxidoreductase gene of Eubacterium sp. VPI 12708 in Escherichia coli.Baron SF, Hylemon PB1995 Jun 127599167
Clostridium scindens baiCD and baiH genes encode stereo-specific 7alpha/7beta-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductases.Kang DJ, Ridlon JM, Moore DR 2nd, Barnes S, Hylemon PB2008 Jan-Feb18047844