| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.3.1.117 |
|---|---|
| Description: | Hydroxycinnamoyl-CoA reductase. |
| Alternative Name: |
Hydroxycinnamoyl-CoA double bond reductase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.3.1.117 |
| BRENDA Enzyme Link: | BRENDA 1.3.1.117 |
| KEGG Enzyme Link: | KEGG1.3.1.117 |
| BioCyc Enzyme Link: | BioCyc 1.3.1.117 |
| ExPASy Enzyme Link: | ExPASy1.3.1.117 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.1.117 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.1.117 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.1.117 |
| IntEnz Enzyme Link: | IntEnz 1.3.1.117 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.1.117 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:56676 | dihydroferuloyl-CoA + NADP(+) = H(+) + NADPH + trans-feruloyl-CoA |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[c;H0;+0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[n+;H0:10](-[*:11]):[cH;+0:12]:1>>[*:5]-[C;H0;+0:6]1=[CH;+0:12]-[N;H0;+0:10](-[*:11])-[CH;+0:9]=[CH;+0:8]-[CH2;+0:7]-1.[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4] |
| Reaction | ![]() |
| Core-to-Core | |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identification and cloning of an NADPH-dependent hydroxycinnamoyl-CoA double bond reductase involved in dihydrochalcone formation in Malus×domestica Borkh. | Ibdah M, Berim A, Martens S, Valderrama AL, Palmieri L, Lewinsohn E, Gang DR | 2014 Nov | 25152451 |
| RHEA:56672 | dihydro-4-coumaroyl-CoA + NADP(+) = H(+) + NADPH + trans-4-coumaroyl-CoA |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[c;H0;+0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[n+;H0:10](-[*:11]):[cH;+0:12]:1>>[*:5]-[C;H0;+0:6]1=[CH;+0:12]-[N;H0;+0:10](-[*:11])-[CH;+0:9]=[CH;+0:8]-[CH2;+0:7]-1.[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4] |
| Reaction | ![]() |
| Core-to-Core | |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identification and cloning of an NADPH-dependent hydroxycinnamoyl-CoA double bond reductase involved in dihydrochalcone formation in Malus×domestica Borkh. | Ibdah M, Berim A, Martens S, Valderrama AL, Palmieri L, Lewinsohn E, Gang DR | 2014 Nov | 25152451 |