Enzyme

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EC Tree
     1. Oxidoreductases
        1.3 Acting on the CH-CH group of donors
            1.3.1 With NAD+ or NADP+ as acceptor
ID:1.3.1.117
Description:Hydroxycinnamoyl-CoA reductase.
Alternative Name: Hydroxycinnamoyl-CoA double bond reductase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.3.1.117
BRENDA Enzyme Link: BRENDA 1.3.1.117
KEGG Enzyme Link: KEGG1.3.1.117
BioCyc Enzyme Link: BioCyc 1.3.1.117
ExPASy Enzyme Link: ExPASy1.3.1.117
EC2PDB Enzyme Link: EC2PDB 1.3.1.117
ExplorEnz Enzyme Link: ExplorEnz 1.3.1.117
PRIAM enzyme-specific profiles Link: PRIAM 1.3.1.117
IntEnz Enzyme Link: IntEnz 1.3.1.117
MEDLINE Enzyme Link: MEDLINE 1.3.1.117
MSA:

1.3.1.117;

Phylogenetic Tree:

1.3.1.117;

Uniprot:
M-CSA:
RHEA:56676 dihydroferuloyl-CoA + NADP(+) = H(+) + NADPH + trans-feruloyl-CoA
RULE(radius=1) [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[c;H0;+0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[n+;H0:10](-[*:11]):[cH;+0:12]:1>>[*:5]-[C;H0;+0:6]1=[CH;+0:12]-[N;H0;+0:10](-[*:11])-[CH;+0:9]=[CH;+0:8]-[CH2;+0:7]-1.[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4]
Reaction
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References

TitleAuthorsDatePubMed ID
Identification and cloning of an NADPH-dependent hydroxycinnamoyl-CoA double bond reductase involved in dihydrochalcone formation in Malus×domestica Borkh.Ibdah M, Berim A, Martens S, Valderrama AL, Palmieri L, Lewinsohn E, Gang DR2014 Nov25152451

RHEA:56672 dihydro-4-coumaroyl-CoA + NADP(+) = H(+) + NADPH + trans-4-coumaroyl-CoA
RULE(radius=1) [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[c;H0;+0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[n+;H0:10](-[*:11]):[cH;+0:12]:1>>[*:5]-[C;H0;+0:6]1=[CH;+0:12]-[N;H0;+0:10](-[*:11])-[CH;+0:9]=[CH;+0:8]-[CH2;+0:7]-1.[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4]
Reaction
Core-to-Core More
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Identification and cloning of an NADPH-dependent hydroxycinnamoyl-CoA double bond reductase involved in dihydrochalcone formation in Malus×domestica Borkh.Ibdah M, Berim A, Martens S, Valderrama AL, Palmieri L, Lewinsohn E, Gang DR2014 Nov25152451