Enzyme

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EC Tree
     1. Oxidoreductases
        1.3 Acting on the CH-CH group of donors
            1.3.1 With NAD+ or NADP+ as acceptor
ID:1.3.1.18
Description:Kynurenate-7,8-dihydrodiol dehydrogenase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.3.1.18
BRENDA Enzyme Link: BRENDA 1.3.1.18
KEGG Enzyme Link: KEGG1.3.1.18
BioCyc Enzyme Link: BioCyc 1.3.1.18
ExPASy Enzyme Link: ExPASy1.3.1.18
EC2PDB Enzyme Link: EC2PDB 1.3.1.18
ExplorEnz Enzyme Link: ExplorEnz 1.3.1.18
PRIAM enzyme-specific profiles Link: PRIAM 1.3.1.18
IntEnz Enzyme Link: IntEnz 1.3.1.18
MEDLINE Enzyme Link: MEDLINE 1.3.1.18
MSA:

1.3.1.18;

Phylogenetic Tree:

1.3.1.18;

Uniprot:
M-CSA:
RHEA:22248 7,8-dihydro-7,8-dihydroxykynurenate + NAD(+) = 7,8-dihydroxykynurenate + H(+) + NADH
RULE(radius=1) [*:1]-[CH;+0:2]1-[CH;+0:3]=[CH;+0:4]-[*:5]:[*:6]-[CH;+0:7]-1-[*:8].[*:9]-[n+;H0:10]1:[cH;+0:11]:[cH;+0:12]:[cH;+0:13]:[c;H0;+0:14](-[*:15]):[cH;+0:16]:1>>[*:9]-[N;H0;+0:10]1-[CH;+0:11]=[CH;+0:12]-[CH2;+0:13]-[C;H0;+0:14](-[*:15])=[CH;+0:16]-1.[*:1]-[c;H0;+0:2]1:[cH;+0:3]:[cH;+0:4]:[*:5]:[*:6]:[c;H0;+0:7]:1-[*:8]
Reaction
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References

TitleAuthorsDatePubMed ID
Studies on the metabolism of kynurenic acid. III. Enzymatic formation of 7,8-dihydroxykynurenic acid from kynurenic acid.TANIUCHI H, HAYAISHI O1963 Jan13984873