EC number:1.3.1.36
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.3.1.36 |
|---|---|
| Description: | Geissoschizine dehydrogenase. |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.1.36 |
| BRENDA Enzyme Link: | BRENDA 1.3.1.36 |
| KEGG Enzyme Link: | KEGG1.3.1.36 |
| BioCyc Enzyme Link: | BioCyc 1.3.1.36 |
| ExPASy Enzyme Link: | ExPASy1.3.1.36 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.1.36 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.1.36 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.1.36 |
| IntEnz Enzyme Link: | IntEnz 1.3.1.36 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.1.36 |
| RHEA:11376 | geissoschizine + NADP(+) = 4,21-dehydrogeissoschizine + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3]-[*:4]-[CH2;+0:5]-[N;H0;+0:6](-[*:7])-[*:8])-[CH;+0:9]=[O;H0;+0:10].[*:11]-[n+;H0:12]1:[cH;+0:13]:[cH;+0:14]:[cH;+0:15]:[c;H0;+0:16](-[*:17]):[cH;+0:18]:1>>[*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[N+;H0:6](-[*:7])-[*:8])=[CH;+0:9]-[OH;+0:10].[*:11]-[N;H0;+0:12]1-[CH;+0:13]=[CH;+0:14]-[CH2;+0:15]-[C;H0;+0:16](-[*:17])=[CH;+0:18]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Geissoschizine synthase controls flux in the formation of monoterpenoid indole alkaloids in a Catharanthus roseus mutant. | Qu Y, Thamm AMK, Czerwinski M, Masada S, Kim KH, Jones G, Liang P, De Luca V | 2018 Mar | 29147812 |