EC number:1.3.1.43
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.3.1.43 | ||
|---|---|---|---|
| Description: | Arogenate dehydrogenase. | ||
| Alternative Name: |
Pretyrosine dehydrogenase. L-arogenate:NAD(+) oxidoreductase. Cyclohexadienyl dehydrogenase. Arogenic dehydrogenase. | ||
| Prosite: | PDOC51176; | ||
| PDB: |
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| Cath: | 1.10.3660.10; 3.40.50.720; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.1.43 |
| BRENDA Enzyme Link: | BRENDA 1.3.1.43 |
| KEGG Enzyme Link: | KEGG1.3.1.43 |
| BioCyc Enzyme Link: | BioCyc 1.3.1.43 |
| ExPASy Enzyme Link: | ExPASy1.3.1.43 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.1.43 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.1.43 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.1.43 |
| IntEnz Enzyme Link: | IntEnz 1.3.1.43 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.1.43 |
| RHEA:12256 | L-arogenate + NAD(+) = CO2 + L-tyrosine + NADH |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1(-[C;H0;+0:3](=[*:4])-[OH;+0:5])-[CH;+0:6]=[CH;+0:7]-[CH;+0:8](-[*:9])-[CH;+0:10]=[CH;+0:11]-1.[*:12]-[n+;H0:13]1:[cH;+0:14]:[cH;+0:15]:[cH;+0:16]:[c;H0;+0:17](-[*:18]):[cH;+0:19]:1>>[*:12]-[N;H0;+0:13]1-[CH;+0:14]=[CH;+0:15]-[CH2;+0:16]-[C;H0;+0:17](-[*:18])=[CH;+0:19]-1.[*:1]-[c;H0;+0:2]1:[cH;+0:6]:[cH;+0:7]:[c;H0;+0:8](-[*:9]):[cH;+0:10]:[cH;+0:11]:1.[*:4]=[C;H0;+0:3]=[O;H0;+0:5] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Variable enzymological patterning in tyrosine biosynthesis as a means of determining natural relatedness among the Pseudomonadaceae. | Byng GS, Whitaker RJ, Gherna RL, Jensen RA | 1980 Oct | 7419490 |
| An allosterically insensitive class of cyclohexadienyl dehydrogenase from Zymomonas mobilis. | Zhao G, Xia T, Ingram LO, Jensen RA | 1993 Feb 15 | 7916685 |
| Cyclohexadienyl dehydrogenase from Pseudomonas stutzeri exemplifies a widespread type of tyrosine-pathway dehydrogenase in the TyrA protein family. | Xie G, Bonner CA, Jensen RA | 2000 Jan | 11790331 |