EC number:1.3.1.5
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.3.1.5 |
|---|---|
| Description: | Cucurbitacin Delta(23)-reductase. |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.1.5 |
| BRENDA Enzyme Link: | BRENDA 1.3.1.5 |
| KEGG Enzyme Link: | KEGG1.3.1.5 |
| BioCyc Enzyme Link: | BioCyc 1.3.1.5 |
| ExPASy Enzyme Link: | ExPASy1.3.1.5 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.1.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.1.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.1.5 |
| IntEnz Enzyme Link: | IntEnz 1.3.1.5 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.1.5 |
| RHEA:20653 | 23,24-dihydrocucurbitacin B + NAD(+) = cucurbitacin B + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cucurbitacin B delta 23-reductase from Cucurbita maxima. I. Assay methods, isolation and purification. | Schabort JC, Potgieter DJ, de Villiers V | 1968 Jan 8 | 5640163 |
| Cucurbitacin B delta 23-reductase from Cucurbita maxima. II. Cofactor requirements, enzyme kinetics, substrate specificity and other characteristics. | Schabort JC, Potgieter DJ | 1968 Jan 8 | 4384331 |
| RHEA:20649 | 23,24-dihydrocucurbitacin B + NADP(+) = cucurbitacin B + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cucurbitacin B delta 23-reductase from Cucurbita maxima. I. Assay methods, isolation and purification. | Schabort JC, Potgieter DJ, de Villiers V | 1968 Jan 8 | 5640163 |
| Cucurbitacin B delta 23-reductase from Cucurbita maxima. II. Cofactor requirements, enzyme kinetics, substrate specificity and other characteristics. | Schabort JC, Potgieter DJ | 1968 Jan 8 | 4384331 |