Enzyme

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     1. Oxidoreductases
        1.3 Acting on the CH-CH group of donors
            1.3.1 With NAD+ or NADP+ as acceptor
ID:1.3.1.56
Description:Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase.
Alternative Name: Biphenyl-2,3-dihydro-2,3-diol dehydrogenase.
2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase.
Prosite: PDOC00060;
PDB:
PDBScop
Cath: 3.40.50.720; 3.10.180.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.3.1.56
BRENDA Enzyme Link: BRENDA 1.3.1.56
KEGG Enzyme Link: KEGG1.3.1.56
BioCyc Enzyme Link: BioCyc 1.3.1.56
ExPASy Enzyme Link: ExPASy1.3.1.56
EC2PDB Enzyme Link: EC2PDB 1.3.1.56
ExplorEnz Enzyme Link: ExplorEnz 1.3.1.56
PRIAM enzyme-specific profiles Link: PRIAM 1.3.1.56
IntEnz Enzyme Link: IntEnz 1.3.1.56
MEDLINE Enzyme Link: MEDLINE 1.3.1.56
MSA:

1.3.1.56;

Phylogenetic Tree:

1.3.1.56;

Uniprot:
M-CSA:
RHEA:17033 (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+) = biphenyl-2,3-diol + H(+) + NADH
RULE(radius=1) [*:1]-[CH;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH;+0:5]=[C;H0;+0:6](-[c;H0;+0:7](:[*:8]):[*:9])-[CH;+0:10]-1-[*:11].[*:12]-[n+;H0:13]1:[cH;+0:14]:[cH;+0:15]:[cH;+0:16]:[c;H0;+0:17](-[*:18]):[cH;+0:19]:1>>[*:12]-[N;H0;+0:13]1-[CH;+0:14]=[CH;+0:15]-[CH2;+0:16]-[C;H0;+0:17](-[*:18])=[CH;+0:19]-1.[*:1]-[c;H0;+0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[c;H0;+0:7](:[*:8]):[*:9]):[c;H0;+0:10]:1-[*:11]
Reaction
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References

TitleAuthorsDatePubMed ID
Crystal structure of cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase from a PCB degrader at 2.0 A resolution.Hülsmeyer M, Hecht HJ, Niefind K, Hofer B, Eltis LD, Timmis KN, Schomburg D1998 Jun9655331
Biochemical studies and ligand-bound structures of biphenyl dehydrogenase from Pandoraea pnomenusa strain B-356 reveal a basis for broad specificity of the enzyme.Dhindwal S, Patil DN, Mohammadi M, Sylvestre M, Tomar S, Kumar P2011 Oct 2121880718