EC number:1.3.1.71
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.3.1.71 |
|---|---|
| Description: | Delta(24(24(1)))-sterol reductase. |
| Alternative Name: |
Sterol Delta(24(28))-reductase. Sterol Delta(24(28))-methylene reductase. C-24(28) sterol reductase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.1.71 |
| BRENDA Enzyme Link: | BRENDA 1.3.1.71 |
| KEGG Enzyme Link: | KEGG1.3.1.71 |
| BioCyc Enzyme Link: | BioCyc 1.3.1.71 |
| ExPASy Enzyme Link: | ExPASy1.3.1.71 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.1.71 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.1.71 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.1.71 |
| IntEnz Enzyme Link: | IntEnz 1.3.1.71 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.1.71 |
| RHEA:18501 | ergosterol + NADP(+) = ergosta-5,7,22,24(28)-tetraen-3beta-ol + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[CH3;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[CH2;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The identification of a gene family in the Saccharomyces cerevisiae ergosterol biosynthesis pathway. | Lai MH, Bard M, Pierson CA, Alexander JF, Goebl M, Carter GT, Kirsch DR | 1994 Mar 11 | 8125337 |
| Sterol 24(28) methylene reductase in Saccharomyces cerevisiae. | Neal WD, Parks LW | 1977 Mar | 14922 |
| Biochemical characterization and subcellular localization of the sterol C-24(28) reductase, erg4p, from the yeast saccharomyces cerevisiae. | Zweytick D, Hrastnik C, Kohlwein SD, Daum G | 2000 Mar 17 | 10722850 |