Enzyme

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     1. Oxidoreductases
        1.3 Acting on the CH-CH group of donors
            1.3.1 With NAD+ or NADP+ as acceptor
ID:1.3.1.75
Description:3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH).
Alternative Name: Plant-type divinyl chlorophyllide a 8-vinyl-reductase.
Divinyl chlorophyllide a 8-vinyl-reductase.
[4-vinyl]chlorophyllide a reductase.
4VCR.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.3.1.75
BRENDA Enzyme Link: BRENDA 1.3.1.75
KEGG Enzyme Link: KEGG1.3.1.75
BioCyc Enzyme Link: BioCyc 1.3.1.75
ExPASy Enzyme Link: ExPASy1.3.1.75
EC2PDB Enzyme Link: EC2PDB 1.3.1.75
ExplorEnz Enzyme Link: ExplorEnz 1.3.1.75
PRIAM enzyme-specific profiles Link: PRIAM 1.3.1.75
IntEnz Enzyme Link: IntEnz 1.3.1.75
MEDLINE Enzyme Link: MEDLINE 1.3.1.75
MSA:

1.3.1.75;

Phylogenetic Tree:

1.3.1.75;

Uniprot:
M-CSA:
RHEA:48884 NADP(+) + protochlorophyllide a = 3,8-divinyl protochlorophyllide a + H(+) + NADPH
RULE(radius=1) [*:1]-[CH2;+0:2]-[CH3;+0:3].[*:4]-[n+;H0:5]1:[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:[c;H0;+0:9](-[*:10]):[cH;+0:11]:1>>[*:1]-[CH;+0:2]=[CH2;+0:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-[C;H0;+0:9](-[*:10])=[CH;+0:11]-1
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Chloroplast biogenesis 72: a [4-vinyl]chlorophyllide a reductase assay using divinyl chlorophyllide a as an exogenous substrate.Parham R, Rebeiz CA1995 Oct 108678296
Chloroplast Biogenesis 60 : Conversion of Divinyl Protochlorophyllide to Monovinyl Protochlorophyllide in Green(ing) Barley, a Dark Monovinyl/Light Divinyl Plant Species.Tripathy BC, Rebeiz CA1988 May16666133
Chloroplast biogenesis: [4-vinyl] chlorophyllide a reductase is a divinyl chlorophyllide a-specific, NADPH-dependent enzyme.Parham R, Rebeiz CA1992 Sep 151390630
Chloroplast biogenesis 84: solubilization and partial purification of membrane-bound [4-vinyl]chlorophyllide a reductase from etiolated barley leaves.Kolossov VL, Rebeiz CA2001 Aug 1511488624
One divinyl reductase reduces the 8-vinyl groups in various intermediates of chlorophyll biosynthesis in a given higher plant species, but the isozyme differs between species.Wang P, Wan C, Xu Z, Wang P, Wang W, Sun C, Ma X, Xiao Y, Zhu J, Gao X, Deng X2013 Jan23154534
Divinyl chlorophyll(ide) a can be converted to monovinyl chlorophyll(ide) a by a divinyl reductase in rice.Wang P, Gao J, Wan C, Zhang F, Xu Z, Huang X, Sun X, Deng X2010 Jul20484022
The major route for chlorophyll synthesis includes [3,8-divinyl]-chlorophyllide a reduction in Arabidopsis thaliana.Nagata N, Tanaka R, Tanaka A2007 Dec17991629
Characterization of a plant-like protochlorophyllide a divinyl reductase in green sulfur bacteria.Chew AG, Bryant DA2007 Feb 217148453
Identification of a vinyl reductase gene for chlorophyll synthesis in Arabidopsis thaliana and implications for the evolution of Prochlorococcus species.Nagata N, Tanaka R, Satoh S, Tanaka A2005 Jan15632054

RHEA:14449 chlorophyllide a + NADP(+) = 3,8-divinyl chlorophyllide a + H(+) + NADPH
RULE(radius=1) [*:1]-[CH2;+0:2]-[CH3;+0:3].[*:4]-[n+;H0:5]1:[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:[c;H0;+0:9](-[*:10]):[cH;+0:11]:1>>[*:1]-[CH;+0:2]=[CH2;+0:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-[C;H0;+0:9](-[*:10])=[CH;+0:11]-1
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Chloroplast biogenesis 72: a [4-vinyl]chlorophyllide a reductase assay using divinyl chlorophyllide a as an exogenous substrate.Parham R, Rebeiz CA1995 Oct 108678296
Chloroplast Biogenesis 60 : Conversion of Divinyl Protochlorophyllide to Monovinyl Protochlorophyllide in Green(ing) Barley, a Dark Monovinyl/Light Divinyl Plant Species.Tripathy BC, Rebeiz CA1988 May16666133
Chloroplast biogenesis: [4-vinyl] chlorophyllide a reductase is a divinyl chlorophyllide a-specific, NADPH-dependent enzyme.Parham R, Rebeiz CA1992 Sep 151390630
Chloroplast biogenesis 84: solubilization and partial purification of membrane-bound [4-vinyl]chlorophyllide a reductase from etiolated barley leaves.Kolossov VL, Rebeiz CA2001 Aug 1511488624