EC number:1.3.1.8
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.3.1.8 |
|---|---|
| Description: | Acyl-CoA dehydrogenase (NADP(+)). |
| Alternative Name: |
Enoyl coenzyme A reductase. 2-enoyl-CoA reductase. |
| Cath: | 3.40.50.720; 3.90.180.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.1.8 |
| BRENDA Enzyme Link: | BRENDA 1.3.1.8 |
| KEGG Enzyme Link: | KEGG1.3.1.8 |
| BioCyc Enzyme Link: | BioCyc 1.3.1.8 |
| ExPASy Enzyme Link: | ExPASy1.3.1.8 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.1.8 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.1.8 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.1.8 |
| IntEnz Enzyme Link: | IntEnz 1.3.1.8 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.1.8 |
| RHEA:22460 | a 2,3-saturated acyl-CoA + NADP(+) = a 2,3-dehydroacyl-CoA + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[c;H0;+0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[n+;H0:10](-[*:11]):[cH;+0:12]:1>>[*:5]-[C;H0;+0:6]1=[CH;+0:12]-[N;H0;+0:10](-[*:11])-[CH;+0:9]=[CH;+0:8]-[CH2;+0:7]-1.[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification by affinity chromatography of 2,4-dienoyl-CoA reductases from bovine liver and Escherichia coli. | Dommes V, Luster W, Cvetanović M, Kunau WH | 1982 Jul | 6749495 |
| On the mechanism of malonyl-CoA-independent fatty acid synthesis. I. The mechanism of elongation of long-chain fatty acids by acetyl-CoA. | Seubert W, Lamberts I, Kramer R, Ohly B | 1968 Dec 18 | 4387390 |