EC number:1.3.1.81
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.3.1.81 |
|---|---|
| Description: | (+)-pulegone reductase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.1.81 |
| BRENDA Enzyme Link: | BRENDA 1.3.1.81 |
| KEGG Enzyme Link: | KEGG1.3.1.81 |
| BioCyc Enzyme Link: | BioCyc 1.3.1.81 |
| ExPASy Enzyme Link: | ExPASy1.3.1.81 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.1.81 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.1.81 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.1.81 |
| IntEnz Enzyme Link: | IntEnz 1.3.1.81 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.1.81 |
| RHEA:25645 | (2R,5R)-isomenthone + NADP(+) = (R)-pulegone + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[CH;+0:4](-[*:5])-[*:6].[*:7]-[n+;H0:8]1:[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:[c;H0;+0:12](-[*:13]):[cH;+0:14]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[C;H0;+0:4](-[*:5])-[*:6].[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[CH;+0:10]-[CH2;+0:11]-[C;H0;+0:12](-[*:13])=[CH;+0:14]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Organization of monoterpene biosynthesis in Mentha. Immunocytochemical localizations of geranyl diphosphate synthase, limonene-6-hydroxylase, isopiperitenol dehydrogenase, and pulegone reductase. | Turner GW, Croteau R | 2004 Dec | 15542490 |
| Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint. | Ringer KL, McConkey ME, Davis EM, Rushing GW, Croteau R | 2003 Oct 1 | 13679086 |
| RHEA:25641 | (1R,4S)-menthone + NADP(+) = (R)-pulegone + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[CH;+0:4](-[*:5])-[*:6].[*:7]-[n+;H0:8]1:[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:[c;H0;+0:12](-[*:13]):[cH;+0:14]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[C;H0;+0:4](-[*:5])-[*:6].[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[CH;+0:10]-[CH2;+0:11]-[C;H0;+0:12](-[*:13])=[CH;+0:14]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Organization of monoterpene biosynthesis in Mentha. Immunocytochemical localizations of geranyl diphosphate synthase, limonene-6-hydroxylase, isopiperitenol dehydrogenase, and pulegone reductase. | Turner GW, Croteau R | 2004 Dec | 15542490 |
| Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint. | Ringer KL, McConkey ME, Davis EM, Rushing GW, Croteau R | 2003 Oct 1 | 13679086 |