Enzyme

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     1. Oxidoreductases
        1.3 Acting on the CH-CH group of donors
            1.3.1 With NAD+ or NADP+ as acceptor
ID:1.3.1.87
Description:3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase.
Alternative Name: Cis-dihydrodiol dehydrogenase.
2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.3.1.87
BRENDA Enzyme Link: BRENDA 1.3.1.87
KEGG Enzyme Link: KEGG1.3.1.87
BioCyc Enzyme Link: BioCyc 1.3.1.87
ExPASy Enzyme Link: ExPASy1.3.1.87
EC2PDB Enzyme Link: EC2PDB 1.3.1.87
ExplorEnz Enzyme Link: ExplorEnz 1.3.1.87
PRIAM enzyme-specific profiles Link: PRIAM 1.3.1.87
IntEnz Enzyme Link: IntEnz 1.3.1.87
MEDLINE Enzyme Link: MEDLINE 1.3.1.87
MSA:

1.3.1.87;

Phylogenetic Tree:

1.3.1.87;

Uniprot:
M-CSA:
RHEA:25066 (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD(+) = (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H(+) + NADH
RULE(radius=1) [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[CH;+0:4]=[CH;+0:5]-[CH;+0:6](-[*:7])-[CH;+0:8]-1-[*:9].[*:10]-[n+;H0:11]1:[cH;+0:12]:[cH;+0:13]:[cH;+0:14]:[c;H0;+0:15](-[*:16]):[cH;+0:17]:1>>[*:10]-[N;H0;+0:11]1-[CH;+0:12]=[CH;+0:13]-[CH2;+0:14]-[C;H0;+0:15](-[*:16])=[CH;+0:17]-1.[*:1]-[c;H0;+0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[c;H0;+0:8]:1-[*:9]
Reaction
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References

TitleAuthorsDatePubMed ID
Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.Díaz E, Ferrández A, García JL1998 Jun9603882

RHEA:25062 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD(+) = 3-(2,3-dihydroxyphenyl)propanoate + H(+) + NADH
RULE(radius=1) [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[CH;+0:4]=[CH;+0:5]-[CH;+0:6](-[*:7])-[CH;+0:8]-1-[*:9].[*:10]-[n+;H0:11]1:[cH;+0:12]:[cH;+0:13]:[cH;+0:14]:[c;H0;+0:15](-[*:16]):[cH;+0:17]:1>>[*:10]-[N;H0;+0:11]1-[CH;+0:12]=[CH;+0:13]-[CH2;+0:14]-[C;H0;+0:15](-[*:16])=[CH;+0:17]-1.[*:1]-[c;H0;+0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[c;H0;+0:8]:1-[*:9]
Reaction
Core-to-Core More
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.Díaz E, Ferrández A, García JL1998 Jun9603882