EC number:1.3.1.92
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.3.1.92 |
|---|---|
| Description: | Artemisinic aldehyde Delta(11(13)) reductase. |
| Cath: | 3.20.20.70; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.1.92 |
| BRENDA Enzyme Link: | BRENDA 1.3.1.92 |
| KEGG Enzyme Link: | KEGG1.3.1.92 |
| BioCyc Enzyme Link: | BioCyc 1.3.1.92 |
| ExPASy Enzyme Link: | ExPASy1.3.1.92 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.1.92 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.1.92 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.1.92 |
| IntEnz Enzyme Link: | IntEnz 1.3.1.92 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.1.92 |
| RHEA:32883 | (11R)-dihydroartemisinic aldehyde + NADP(+) = (+)-artemisinic aldehyde + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[CH3;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[CH2;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The molecular cloning of artemisinic aldehyde Delta11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua. | Zhang Y, Teoh KH, Reed DW, Maes L, Goossens A, Olson DJ, Ross AR, Covello PS | 2008 Aug 1 | 18495659 |
| Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua. | Bertea CM, Freije JR, van der Woude H, Verstappen FW, Perk L, Marquez V, De Kraker JW, Posthumus MA, Jansen BJ, de Groot A, Franssen MC, Bouwmeester HJ | 2005 Jan | 15678372 |