EC number:1.3.3.5
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.3 With oxygen as acceptor |
| ID: | 1.3.3.5 |
|---|---|
| Description: | Bilirubin oxidase. |
| Cath: | 2.60.40.420; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.3.5 |
| BRENDA Enzyme Link: | BRENDA 1.3.3.5 |
| KEGG Enzyme Link: | KEGG1.3.3.5 |
| BioCyc Enzyme Link: | BioCyc 1.3.3.5 |
| ExPASy Enzyme Link: | ExPASy1.3.3.5 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.3.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.3.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.3.5 |
| IntEnz Enzyme Link: | IntEnz 1.3.3.5 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.3.5 |
| RHEA:20980 | 2 bilirubin IXalpha + O2 = 2 biliverdin IXalpha + 2 H2O |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[c;H0;+0:3]1:[nH;+0:4]:[c;H0;+0:5](-[*:6]):[c;H0;+0:7](-[*:8]):[c;H0;+0:9]:1-[*:10].[*:11]-[c;H0;+0:12]1:[nH;+0:13]:[c;H0;+0:14](-[CH2;+0:15]-[*:16]):[c;H0;+0:17](-[*:18]):[c;H0;+0:19]:1-[*:20].[O;H0;+0:21]=[O;H0;+0:22]>>[*:11]-[C;H0;+0:12]1=[N;H0;+0:13]-[C;H0;+0:14](=[CH;+0:15]-[*:16])-[C;H0;+0:17](-[*:18])=[C;H0;+0:19]-1-[*:20].[*:1]-[CH;+0:2]=[C;H0;+0:3]1-[N;H0;+0:4]=[C;H0;+0:5](-[*:6])-[C;H0;+0:7](-[*:8])=[C;H0;+0:9]-1-[*:10].[OH2;+0:21].[OH2;+0:22] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Molecular cloning of the gene for bilirubin oxidase from Myrothecium verrucaria and its expression in yeast. | Koikeda S, Ando K, Kaji H, Inoue T, Murao S, Takeuchi K, Samejima T | 1993 Sep 5 | 8360171 |
| Bilirubin oxidase from Myrothecium verrucaria: X-ray determination of the complete crystal structure and a rational surface modification for enhanced electrocatalytic O2 reduction. | Cracknell JA, McNamara TP, Lowe ED, Blanford CF | 2011 Jul 7 | 21544308 |
| X-ray analysis of bilirubin oxidase from Myrothecium verrucaria at 2.3 A resolution using a twinned crystal. | Mizutani K, Toyoda M, Sagara K, Takahashi N, Sato A, Kamitaka Y, Tsujimura S, Nakanishi Y, Sugiura T, Yamaguchi S, Kano K, Mikami B | 2010 Jul 1 | 20606269 |