EC number:1.3.7.1

Enzyme

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EC Tree
     1. Oxidoreductases
        1.3 Acting on the CH-CH group of donors
            1.3.7 With an iron-sulfur protein as acceptor
ID:1.3.7.1
Description:6-hydroxynicotinate reductase.
Alternative Name: HNA reductase.
6-oxotetrahydro-nicotinate dehydrogenase.
6-hydroxynicotinic reductase.
Cath: 1.10.1040.10; 1.10.150.120; 3.20.20.140; 3.30.365.10; 3.30.390.50; 3.30.465.10; 3.40.50.720; 2.30.40.10; 3.40.50.12340; 3.10.20.30;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.3.7.1
BRENDA Enzyme Link: BRENDA 1.3.7.1
KEGG Enzyme Link: KEGG1.3.7.1
BioCyc Enzyme Link: BioCyc 1.3.7.1
ExPASy Enzyme Link: ExPASy1.3.7.1
EC2PDB Enzyme Link: EC2PDB 1.3.7.1
ExplorEnz Enzyme Link: ExplorEnz 1.3.7.1
PRIAM enzyme-specific profiles Link: PRIAM 1.3.7.1
IntEnz Enzyme Link: IntEnz 1.3.7.1
MEDLINE Enzyme Link: MEDLINE 1.3.7.1

EC number:1.3.7.1

MSA:

1.3.7.1;
Phylogenetic Tree:

1.3.7.1;
Uniprot:
M-CSA:
RHEA:17225 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized 2[4Fe-4S]-[ferredoxin] = 6-hydroxynicotinate + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin]
RULE(radius=1) [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[NH;+0:4]-[C;H0;+0:5](=[O;H0;+0:6])-[CH2;+0:7]-[CH2;+0:8]-1>>[*:1]-[c;H0;+0:2]1:[cH;+0:8]:[cH;+0:7]:[c;H0;+0:5](-[OH;+0:6]):[n;H0;+0:4]:[cH;+0:3]:1
Reaction
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References

TitleAuthorsDatePubMed ID
Nicotinic acid metabolism. IV. Ferredoxin-dependent reduction of 6-hydroxynicotinic acid to 6-oxo-1,4,5,6-tetrahydronicotinic acid.Holcenberg JS, Tsai L1969 Mar 105767303