Enzyme

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EC Tree
     1. Oxidoreductases
        1.3 Acting on the CH-CH group of donors
            1.3.8 With a flavin as acceptor
ID:1.3.8.3
Description:(R)-benzylsuccinyl-CoA dehydrogenase.
Prosite: PDOC00070;
PDB:
PDBScop
1RX0 8028591; 8028593; 8040970; 8040972; 8028591; 8028593; 8040970; 8040972; 8028591; 8028593; 8040970; 8040972; 8028591; 8028593; 8040970; 8040972;
2R0N 8027101; 8027104; 8039480; 8039483;
2R0M 8027101; 8027104; 8039480; 8039483;
1SIR 8027101; 8027104; 8039480; 8039483;
1SIQ 8027101; 8027104; 8039480; 8039483;
 » show all

Cath: 1.10.540.10; 1.20.140.10; 2.40.110.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.3.8.3
BRENDA Enzyme Link: BRENDA 1.3.8.3
KEGG Enzyme Link: KEGG1.3.8.3
BioCyc Enzyme Link: BioCyc 1.3.8.3
ExPASy Enzyme Link: ExPASy1.3.8.3
EC2PDB Enzyme Link: EC2PDB 1.3.8.3
ExplorEnz Enzyme Link: ExplorEnz 1.3.8.3
PRIAM enzyme-specific profiles Link: PRIAM 1.3.8.3
IntEnz Enzyme Link: IntEnz 1.3.8.3
MEDLINE Enzyme Link: MEDLINE 1.3.8.3
MSA:

1.3.8.3;

Phylogenetic Tree:

1.3.8.3;

Uniprot:
M-CSA:
RHEA:20876 (R)-2-benzylsuccinyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (E)-2-benzylidenesuccinyl-CoA + reduced [electron-transfer flavoprotein]
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[CH2;+0:4]-[*:5].[*:6]:[c;H0;+0:7]1:[n;H0;+0:8]:[*:9]:[*:10]:[n;H0;+0:11](-[*:12]):[c;H0;+0:13]-1:[n;H0;+0:14]:[*:15].[H+;H0:16]>>[*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:4]-[*:5].[*:6]:[c;H0;+0:7]1:[c;H0;+0:13](:[nH;+0:14]:[*:15])-[N;H0;+0:11](-[*:12])-[*:10]:[*:9]-[NH;+0:8]-1
Reaction
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References

TitleAuthorsDatePubMed ID
(R)-Benzylsuccinyl-CoA dehydrogenase of Thauera aromatica, an enzyme of the anaerobic toluene catabolic pathway.Leutwein C, Heider J2002 Dec12420174
Anaerobic toluene-catabolic pathway in denitrifying Thauera aromatica: activation and beta-oxidation of the first intermediate, (R)-(+)-benzylsuccinate.Leutwein C, Heider J1999 Nov10589736