EC number:1.3.99.17

Enzyme

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     1. Oxidoreductases
        1.3 Acting on the CH-CH group of donors
            1.3.99 With unknown physiological acceptors
ID:1.3.99.17
Description:Quinoline 2-oxidoreductase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.3.99.17
BRENDA Enzyme Link: BRENDA 1.3.99.17
KEGG Enzyme Link: KEGG1.3.99.17
BioCyc Enzyme Link: BioCyc 1.3.99.17
ExPASy Enzyme Link: ExPASy1.3.99.17
EC2PDB Enzyme Link: EC2PDB 1.3.99.17
ExplorEnz Enzyme Link: ExplorEnz 1.3.99.17
PRIAM enzyme-specific profiles Link: PRIAM 1.3.99.17
IntEnz Enzyme Link: IntEnz 1.3.99.17
MEDLINE Enzyme Link: MEDLINE 1.3.99.17

EC number:1.3.99.17

MSA:

1.3.99.17;
Phylogenetic Tree:

1.3.99.17;
Uniprot:
M-CSA:
RHEA:17749 A + H2O + quinoline = AH2 + quinolin-2(1H)-one
RULE(radius=1) [*:1]:[n;H0;+0:2]:[cH;+0:3]:[*:4].[OH2;+0:5]>>[*:1]:[nH;+0:2]:[c;H0;+0:3](:[*:4])=[O;H0;+0:5]
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References

TitleAuthorsDatePubMed ID
Quinoline oxidoreductase from Pseudomonas putida 86: an improved purification procedure and electron paramagnetic resonance spectroscopy.Tshisuaka B, Kappl R, Hüttermann J, Lingens F1993 Nov 308251516
Quinoline 2-oxidoreductase and 2-oxo-1,2-dihydroquinoline 5,6-dioxygenase from Comamonas testosteroni 63. The first two enzymes in quinoline and 3-methylquinoline degradation.Schach S, Tshisuaka B, Fetzner S, Lingens F1995 Sep 17556204
Microbial metabolism of quinoline and related compounds. VII. Quinoline oxidoreductase from Pseudomonas putida: a molybdenum-containing enzyme.Bauder R, Tshisuaka B, Lingens F1990 Dec2090161
Microbial metabolism of quinoline and related compounds. XII. Isolation and characterization of the quinoline oxidoreductase from Rhodococcus spec. B1 compared with the quinoline oxidoreductase from Pseudomonas putida 86.Peschke B, Lingens F1991 Dec1789933
Active site geometry and substrate recognition of the molybdenum hydroxylase quinoline 2-oxidoreductase.Bonin I, Martins BM, Purvanov V, Fetzner S, Huber R, Dobbek H2004 Aug15296736
RHEA:25912 A + H2O + quinolin-5-ol = 5-hydroxyquinolin-2(1H)-one + AH2
RULE(radius=1) [*:1]:[n;H0;+0:2]:[cH;+0:3]:[*:4].[OH2;+0:5]>>[*:1]:[nH;+0:2]:[c;H0;+0:3](:[*:4])=[O;H0;+0:5]
Reaction
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References

TitleAuthorsDatePubMed ID
Microbial metabolism of quinoline and related compounds. VII. Quinoline oxidoreductase from Pseudomonas putida: a molybdenum-containing enzyme.Bauder R, Tshisuaka B, Lingens F1990 Dec2090161
RHEA:25916 A + H2O + quinolin-6-ol = 6-hydroxyquinolin-2(1H)-one + AH2
RULE(radius=1) [*:1]:[n;H0;+0:2]:[cH;+0:3]:[*:4].[OH2;+0:5]>>[*:1]:[nH;+0:2]:[c;H0;+0:3](:[*:4])=[O;H0;+0:5]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Microbial metabolism of quinoline and related compounds. VII. Quinoline oxidoreductase from Pseudomonas putida: a molybdenum-containing enzyme.Bauder R, Tshisuaka B, Lingens F1990 Dec2090161
RHEA:25920 A + H2O + quinolin-7-ol = 7-hydroxyquinolin-2(1H)-one + AH2
RULE(radius=1) [*:1]:[n;H0;+0:2]:[cH;+0:3]:[*:4].[OH2;+0:5]>>[*:1]:[nH;+0:2]:[c;H0;+0:3](:[*:4])=[O;H0;+0:5]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Microbial metabolism of quinoline and related compounds. VII. Quinoline oxidoreductase from Pseudomonas putida: a molybdenum-containing enzyme.Bauder R, Tshisuaka B, Lingens F1990 Dec2090161
RHEA:25924 A + H2O + quinolin-8-ol = 8-hydroxyquinolin-2(1H)-one + AH2
RULE(radius=1) [*:1]:[n;H0;+0:2]:[cH;+0:3]:[*:4].[OH2;+0:5]>>[*:1]:[nH;+0:2]:[c;H0;+0:3](:[*:4])=[O;H0;+0:5]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Microbial metabolism of quinoline and related compounds. VII. Quinoline oxidoreductase from Pseudomonas putida: a molybdenum-containing enzyme.Bauder R, Tshisuaka B, Lingens F1990 Dec2090161
RHEA:25928 3-methylquinoline + A + H2O = 3-methylquinolin-2(1H)-one + AH2
RULE(radius=1) [*:1]:[n;H0;+0:2]:[cH;+0:3]:[*:4].[OH2;+0:5]>>[*:1]:[nH;+0:2]:[c;H0;+0:3](:[*:4])=[O;H0;+0:5]
Reaction
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References

TitleAuthorsDatePubMed ID
Microbial metabolism of quinoline and related compounds. VII. Quinoline oxidoreductase from Pseudomonas putida: a molybdenum-containing enzyme.Bauder R, Tshisuaka B, Lingens F1990 Dec2090161
RHEA:25932 4-methylquinoline + A + H2O = 4-methylquinolin-2(1H)-one + AH2
RULE(radius=1) [*:1]:[n;H0;+0:2]:[cH;+0:3]:[*:4].[OH2;+0:5]>>[*:1]:[nH;+0:2]:[c;H0;+0:3](:[*:4])=[O;H0;+0:5]
Reaction
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References

TitleAuthorsDatePubMed ID
Microbial metabolism of quinoline and related compounds. VII. Quinoline oxidoreductase from Pseudomonas putida: a molybdenum-containing enzyme.Bauder R, Tshisuaka B, Lingens F1990 Dec2090161
RHEA:25936 8-methylquinoline + A + H2O = 8-methylquinolin-2(1H)-one + AH2
RULE(radius=1) [*:1]:[n;H0;+0:2]:[cH;+0:3]:[*:4].[OH2;+0:5]>>[*:1]:[nH;+0:2]:[c;H0;+0:3](:[*:4])=[O;H0;+0:5]
Reaction
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References

TitleAuthorsDatePubMed ID
Microbial metabolism of quinoline and related compounds. VII. Quinoline oxidoreductase from Pseudomonas putida: a molybdenum-containing enzyme.Bauder R, Tshisuaka B, Lingens F1990 Dec2090161
RHEA:25940 8-chloroquinoline + A + H2O = 8-chloroquinolin-2(1H)-one + AH2
RULE(radius=1) [*:1]:[n;H0;+0:2]:[cH;+0:3]:[*:4].[OH2;+0:5]>>[*:1]:[nH;+0:2]:[c;H0;+0:3](:[*:4])=[O;H0;+0:5]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Microbial metabolism of quinoline and related compounds. VII. Quinoline oxidoreductase from Pseudomonas putida: a molybdenum-containing enzyme.Bauder R, Tshisuaka B, Lingens F1990 Dec2090161