EC number:1.4.1.1

Enzyme

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EC Tree
     1. Oxidoreductases
        1.4 Acting on the CH-NH2 group of donors
            1.4.1 With NAD+ or NADP+ as acceptor
ID:1.4.1.1
Description:Alanine dehydrogenase.
Prosite: PDOC00654;
PDB:
PDBScop
1L7E 8057720; 8057721; 8057720; 8057721; 8057720; 8057721; 8057720; 8057721;
1L7D 8057720; 8057721; 8057720; 8057721; 8057720; 8057721; 8057720; 8057721;
1F8G 8057720; 8057721; 8057720; 8057721; 8057720; 8057721; 8057720; 8057721;
1U28 8057720; 8057721; 8057720; 8057721; 8026645; 8039024;
1PTJ 8057720; 8057721; 8057720; 8057721; 8026645; 8039024;
 » show all
Cath: 3.30.1780.10; 3.40.50.720;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.4.1.1
BRENDA Enzyme Link: BRENDA 1.4.1.1
KEGG Enzyme Link: KEGG1.4.1.1
BioCyc Enzyme Link: BioCyc 1.4.1.1
ExPASy Enzyme Link: ExPASy1.4.1.1
EC2PDB Enzyme Link: EC2PDB 1.4.1.1
ExplorEnz Enzyme Link: ExplorEnz 1.4.1.1
PRIAM enzyme-specific profiles Link: PRIAM 1.4.1.1
IntEnz Enzyme Link: IntEnz 1.4.1.1
MEDLINE Enzyme Link: MEDLINE 1.4.1.1

EC number:1.4.1.1

MSA:

1.4.1.1;
Phylogenetic Tree:

1.4.1.1;
Uniprot:
M-CSA:
RHEA:18405 H2O + L-alanine + NAD(+) = H(+) + NADH + NH4(+) + pyruvate
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[NH2;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1.[OH2;+0:13]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:13].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1.[NH3;+0:4]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Analysis of the structure and substrate binding of Phormidium lapideum alanine dehydrogenase.Baker PJ, Sawa Y, Shibata H, Sedelnikova SE, Rice DW1998 Jul9665169