Enzyme

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EC Tree
     1. Oxidoreductases
        1.4 Acting on the CH-NH2 group of donors
            1.4.1 With NAD+ or NADP+ as acceptor
ID:1.4.1.15
Description:Lysine dehydrogenase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.4.1.15
BRENDA Enzyme Link: BRENDA 1.4.1.15
KEGG Enzyme Link: KEGG1.4.1.15
BioCyc Enzyme Link: BioCyc 1.4.1.15
ExPASy Enzyme Link: ExPASy1.4.1.15
EC2PDB Enzyme Link: EC2PDB 1.4.1.15
ExplorEnz Enzyme Link: ExplorEnz 1.4.1.15
PRIAM enzyme-specific profiles Link: PRIAM 1.4.1.15
IntEnz Enzyme Link: IntEnz 1.4.1.15
MEDLINE Enzyme Link: MEDLINE 1.4.1.15
MSA:

1.4.1.15;

Phylogenetic Tree:

1.4.1.15;

Uniprot:
M-CSA:
RHEA:18505 L-lysine + NAD(+) = Delta(1)-piperideine-2-carboxylate + H(+) + NADH + NH4(+)
RULE(radius=1) ([*:1]-[CH;+0:2](-[*:3])-[NH2;+0:4].[*:5]-[NH2;+0:6]).[*:7]-[n+;H0:8]1:[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:[c;H0;+0:12](-[*:13]):[cH;+0:14]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[N;H0;+0:6]-[*:5].[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[CH;+0:10]-[CH2;+0:11]-[C;H0;+0:12](-[*:13])=[CH;+0:14]-1.[NH3;+0:4]
Reaction
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References

TitleAuthorsDatePubMed ID
L-Lysine dehydrogenase deficiency in a patient with congenital lysine intolerance.Bürgi W, Richterich R, Colombo JP1966 Aug 204291003