| EC Tree |
| 1. Oxidoreductases |
| 1.4 Acting on the CH-NH2 group of donors |
| 1.4.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.4.1.15 |
|---|---|
| Description: | Lysine dehydrogenase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.4.1.15 |
| BRENDA Enzyme Link: | BRENDA 1.4.1.15 |
| KEGG Enzyme Link: | KEGG1.4.1.15 |
| BioCyc Enzyme Link: | BioCyc 1.4.1.15 |
| ExPASy Enzyme Link: | ExPASy1.4.1.15 |
| EC2PDB Enzyme Link: | EC2PDB 1.4.1.15 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.4.1.15 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.4.1.15 |
| IntEnz Enzyme Link: | IntEnz 1.4.1.15 |
| MEDLINE Enzyme Link: | MEDLINE 1.4.1.15 |
| RHEA:18505 | L-lysine + NAD(+) = Delta(1)-piperideine-2-carboxylate + H(+) + NADH + NH4(+) |
| RULE(radius=1) | ([*:1]-[CH;+0:2](-[*:3])-[NH2;+0:4].[*:5]-[NH2;+0:6]).[*:7]-[n+;H0:8]1:[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:[c;H0;+0:12](-[*:13]):[cH;+0:14]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[N;H0;+0:6]-[*:5].[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[CH;+0:10]-[CH2;+0:11]-[C;H0;+0:12](-[*:13])=[CH;+0:14]-1.[NH3;+0:4] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| L-Lysine dehydrogenase deficiency in a patient with congenital lysine intolerance. | Bürgi W, Richterich R, Colombo JP | 1966 Aug 20 | 4291003 |