EC number:1.4.1.19

Enzyme

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EC Tree
     1. Oxidoreductases
        1.4 Acting on the CH-NH2 group of donors
            1.4.1 With NAD+ or NADP+ as acceptor
ID:1.4.1.19
Description:Tryptophan dehydrogenase.
Alternative Name: TrpDH.
L-tryptophan dehydrogenase.
L-Trp-dehydrogenase.
Cath: 3.40.50.720; 3.40.50.10860;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.4.1.19
BRENDA Enzyme Link: BRENDA 1.4.1.19
KEGG Enzyme Link: KEGG1.4.1.19
BioCyc Enzyme Link: BioCyc 1.4.1.19
ExPASy Enzyme Link: ExPASy1.4.1.19
EC2PDB Enzyme Link: EC2PDB 1.4.1.19
ExplorEnz Enzyme Link: ExplorEnz 1.4.1.19
PRIAM enzyme-specific profiles Link: PRIAM 1.4.1.19
IntEnz Enzyme Link: IntEnz 1.4.1.19
MEDLINE Enzyme Link: MEDLINE 1.4.1.19

EC number:1.4.1.19

MSA:

1.4.1.19;
Phylogenetic Tree:

1.4.1.19;
Uniprot:
M-CSA:
RHEA:13477 H2O + L-tryptophan + NADP(+) = H(+) + indole-3-pyruvate + NADPH + NH4(+)
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[NH2;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1.[OH2;+0:13]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:13].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1.[NH3;+0:4]
Reaction
Core-to-Core More
RHEA:13473 H2O + L-tryptophan + NAD(+) = H(+) + indole-3-pyruvate + NADH + NH4(+)
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[NH2;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1.[OH2;+0:13]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:13].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1.[NH3;+0:4]
Reaction
Core-to-Core More