EC number:1.4.1.23
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.4 Acting on the CH-NH2 group of donors |
| 1.4.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.4.1.23 |
|---|---|
| Description: | Valine dehydrogenase (NAD(+)). |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.4.1.23 |
| BRENDA Enzyme Link: | BRENDA 1.4.1.23 |
| KEGG Enzyme Link: | KEGG1.4.1.23 |
| BioCyc Enzyme Link: | BioCyc 1.4.1.23 |
| ExPASy Enzyme Link: | ExPASy1.4.1.23 |
| EC2PDB Enzyme Link: | EC2PDB 1.4.1.23 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.4.1.23 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.4.1.23 |
| IntEnz Enzyme Link: | IntEnz 1.4.1.23 |
| MEDLINE Enzyme Link: | MEDLINE 1.4.1.23 |
| RHEA:30763 | H2O + L-valine + NAD(+) = 3-methyl-2-oxobutanoate + H(+) + NADH + NH4(+) |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[NH2;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1.[OH2;+0:13]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:13].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1.[NH3;+0:4] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Isolation and characterization of valine dehydrogenase from Streptomyces aureofaciens. | Vancurová I, Vancura A, Volc J, Neuzil J, Flieger M, Basarová G, Bĕhal V | 1988 Nov | 3182727 |
| Purification and catalytic properties of L-valine dehydrogenase from Streptomyces cinnamonensis. | Priestley ND, Robinson JA | 1989 Aug 1 | 2803248 |
| Purification of an inducible L-valine dehydrogenase of Streptomyces coelicolor A3(2). | Navarrete RM, Vara JA, Hutchinson CR | 1990 Feb | 2324704 |