Enzyme

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EC Tree
     1. Oxidoreductases
        1.4 Acting on the CH-NH2 group of donors
            1.4.1 With NAD+ or NADP+ as acceptor
ID:1.4.1.24
Description:3-dehydroquinate synthase II.
Alternative Name: DHQ synthase II.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.4.1.24
BRENDA Enzyme Link: BRENDA 1.4.1.24
KEGG Enzyme Link: KEGG1.4.1.24
BioCyc Enzyme Link: BioCyc 1.4.1.24
ExPASy Enzyme Link: ExPASy1.4.1.24
EC2PDB Enzyme Link: EC2PDB 1.4.1.24
ExplorEnz Enzyme Link: ExplorEnz 1.4.1.24
PRIAM enzyme-specific profiles Link: PRIAM 1.4.1.24
IntEnz Enzyme Link: IntEnz 1.4.1.24
MEDLINE Enzyme Link: MEDLINE 1.4.1.24
MSA:

1.4.1.24;

Phylogenetic Tree:

1.4.1.24;

Uniprot:
M-CSA:
RHEA:25956 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + H2O + NAD(+) = 3-dehydroquinate + H(+) + NADH + NH4(+)
RULE(radius=1) ([*:1]-[CH3;+0:2].[*:3]-[CH;+0:4](-[*:5])-[NH2;+0:6]).[*:7]-[n+;H0:8]1:[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:[c;H0;+0:12](-[*:13]):[cH;+0:14]:1.[OH2;+0:15]>>[*:3]-[C;H0;+0:4](-[*:5])(-[OH;+0:15])-[CH2;+0:2]-[*:1].[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[CH;+0:10]-[CH2;+0:11]-[C;H0;+0:12](-[*:13])=[CH;+0:14]-1.[NH3;+0:6]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
L-Aspartate semialdehyde and a 6-deoxy-5-ketohexose 1-phosphate are the precursors to the aromatic amino acids in Methanocaldococcus jannaschii.White RH2004 Jun 1515182204