EC number:1.4.1.26

Enzyme

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EC Tree
     1. Oxidoreductases
        1.4 Acting on the CH-NH2 group of donors
            1.4.1 With NAD+ or NADP+ as acceptor
ID:1.4.1.26
Description:2,4-diaminopentanoate dehydrogenase (NAD(+)).
Alternative Name: DAPDH.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.4.1.26
BRENDA Enzyme Link: BRENDA 1.4.1.26
KEGG Enzyme Link: KEGG1.4.1.26
BioCyc Enzyme Link: BioCyc 1.4.1.26
ExPASy Enzyme Link: ExPASy1.4.1.26
EC2PDB Enzyme Link: EC2PDB 1.4.1.26
ExplorEnz Enzyme Link: ExplorEnz 1.4.1.26
PRIAM enzyme-specific profiles Link: PRIAM 1.4.1.26
IntEnz Enzyme Link: IntEnz 1.4.1.26
MEDLINE Enzyme Link: MEDLINE 1.4.1.26

EC number:1.4.1.26

MSA:

1.4.1.26;
Phylogenetic Tree:

1.4.1.26;
Uniprot:
M-CSA:
RHEA:24196 (2R,4S)-2,4-diaminopentanoate + H2O + NAD(+) = (2R)-2-amino-4-oxopentanoate + H(+) + NADH + NH4(+)
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[NH2;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1.[OH2;+0:13]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:13].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1.[NH3;+0:4]
Reaction
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References

TitleAuthorsDatePubMed ID
2,4-diaminopentanoic acid C 4 dehydrogenase. Purification and properties of the protein.Somack R, Costilow RN1973 Jan 254684685
Ornithine metabolism by Clostridium sticklandii. Oxidation of ornithine to 2-amino-4-ketopentanoic acid via 2,4-diaminopentanoic acid; participation of B12 coenzyme, pyridoxal phosphate, and pyridine nucleotide.Tsuda Y, Friedmann HC1970 Nov 254394942
A conserved gene cluster rules anaerobic oxidative degradation of L-ornithine.Fonknechten N, Perret A, Perchat N, Tricot S, Lechaplais C, Vallenet D, Vergne C, Zaparucha A, Le Paslier D, Weissenbach J, Salanoubat M2009 May19251850