| EC Tree |
| 1. Oxidoreductases |
| 1.5 Acting on the CH-NH group of donors |
| 1.5.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.5.1.31 |
|---|---|
| Description: | Berberine reductase. |
| Alternative Name: |
(R)-canadine synthase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.5.1.31 |
| BRENDA Enzyme Link: | BRENDA 1.5.1.31 |
| KEGG Enzyme Link: | KEGG1.5.1.31 |
| BioCyc Enzyme Link: | BioCyc 1.5.1.31 |
| ExPASy Enzyme Link: | ExPASy1.5.1.31 |
| EC2PDB Enzyme Link: | EC2PDB 1.5.1.31 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.5.1.31 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.5.1.31 |
| IntEnz Enzyme Link: | IntEnz 1.5.1.31 |
| MEDLINE Enzyme Link: | MEDLINE 1.5.1.31 |
| RHEA:21268 | (R)-canadine + 2 NADP(+) = berberine + H(+) + 2 NADPH |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH2;+0:3]-[*:4]:[*:5]-[CH2;+0:6]-[CH;+0:7]-1-[c;H0;+0:8](:[*:9]):[*:10].[*:11]-[c;H0;+0:12]1:[cH;+0:13]:[cH;+0:14]:[cH;+0:15]:[n+;H0:16](-[*:17]):[cH;+0:18]:1.[*:19]-[n+;H0:20]1:[cH;+0:21]:[cH;+0:22]:[cH;+0:23]:[c;H0;+0:24](-[*:25]):[cH;+0:26]:1>>[*:11]-[C;H0;+0:12]1=[CH;+0:18]-[N;H0;+0:16](-[*:17])-[CH;+0:15]=[CH;+0:14]-[CH2;+0:13]-1.[*:19]-[N;H0;+0:20]1-[CH;+0:21]=[CH;+0:22]-[CH2;+0:23]-[C;H0;+0:24](-[*:25])=[CH;+0:26]-1.[*:1]-[n+;H0:2]1:[cH;+0:3]:[*:4]:[*:5]:[cH;+0:6]:[c;H0;+0:7]:1-[c;H0;+0:8](:[*:9]):[*:10] |
| Reaction | ![]() |
| Core-to-Core | |
| Core-to-Core |