Enzyme

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     1. Oxidoreductases
        1.5 Acting on the CH-NH group of donors
            1.5.1 With NAD+ or NADP+ as acceptor
ID:1.5.1.31
Description:Berberine reductase.
Alternative Name: (R)-canadine synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.5.1.31
BRENDA Enzyme Link: BRENDA 1.5.1.31
KEGG Enzyme Link: KEGG1.5.1.31
BioCyc Enzyme Link: BioCyc 1.5.1.31
ExPASy Enzyme Link: ExPASy1.5.1.31
EC2PDB Enzyme Link: EC2PDB 1.5.1.31
ExplorEnz Enzyme Link: ExplorEnz 1.5.1.31
PRIAM enzyme-specific profiles Link: PRIAM 1.5.1.31
IntEnz Enzyme Link: IntEnz 1.5.1.31
MEDLINE Enzyme Link: MEDLINE 1.5.1.31
MSA:

1.5.1.31;

Phylogenetic Tree:

1.5.1.31;

Uniprot:
M-CSA:
RHEA:21268 (R)-canadine + 2 NADP(+) = berberine + H(+) + 2 NADPH
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH2;+0:3]-[*:4]:[*:5]-[CH2;+0:6]-[CH;+0:7]-1-[c;H0;+0:8](:[*:9]):[*:10].[*:11]-[c;H0;+0:12]1:[cH;+0:13]:[cH;+0:14]:[cH;+0:15]:[n+;H0:16](-[*:17]):[cH;+0:18]:1.[*:19]-[n+;H0:20]1:[cH;+0:21]:[cH;+0:22]:[cH;+0:23]:[c;H0;+0:24](-[*:25]):[cH;+0:26]:1>>[*:11]-[C;H0;+0:12]1=[CH;+0:18]-[N;H0;+0:16](-[*:17])-[CH;+0:15]=[CH;+0:14]-[CH2;+0:13]-1.[*:19]-[N;H0;+0:20]1-[CH;+0:21]=[CH;+0:22]-[CH2;+0:23]-[C;H0;+0:24](-[*:25])=[CH;+0:26]-1.[*:1]-[n+;H0:2]1:[cH;+0:3]:[*:4]:[*:5]:[cH;+0:6]:[c;H0;+0:7]:1-[c;H0;+0:8](:[*:9]):[*:10]
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