Enzyme

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EC Tree
     1. Oxidoreductases
        1.5 Acting on the CH-NH group of donors
            1.5.1 With NAD+ or NADP+ as acceptor
ID:1.5.1.44
Description:Festuclavine dehydrogenase.
Alternative Name: Festuclavine synthase.
Cath: 3.20.20.70;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.5.1.44
BRENDA Enzyme Link: BRENDA 1.5.1.44
KEGG Enzyme Link: KEGG1.5.1.44
BioCyc Enzyme Link: BioCyc 1.5.1.44
ExPASy Enzyme Link: ExPASy1.5.1.44
EC2PDB Enzyme Link: EC2PDB 1.5.1.44
ExplorEnz Enzyme Link: ExplorEnz 1.5.1.44
PRIAM enzyme-specific profiles Link: PRIAM 1.5.1.44
IntEnz Enzyme Link: IntEnz 1.5.1.44
MEDLINE Enzyme Link: MEDLINE 1.5.1.44
MSA:

1.5.1.44;

Phylogenetic Tree:

1.5.1.44;

Uniprot:
M-CSA:
RHEA:34055 festuclavine + NAD(+) = 6,8-dimethyl-6,7-didehydroergoline + H(+) + NADH
RULE(radius=1) [*:1]-[CH2;+0:2]-[N;H0;+0:3](-[*:4])-[*:5].[*:6]-[n+;H0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[c;H0;+0:11](-[*:12]):[cH;+0:13]:1>>[*:1]-[CH;+0:2]=[N+;H0:3](-[*:4])-[*:5].[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[CH;+0:9]-[CH2;+0:10]-[C;H0;+0:11](-[*:12])=[CH;+0:13]-1
Reaction
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References

TitleAuthorsDatePubMed ID
Ergot alkaloid biosynthesis in Aspergillus fumigatus: Conversion of chanoclavine-I aldehyde to festuclavine by the festuclavine synthase FgaFS in the presence of the old yellow enzyme FgaOx3.Wallwey C, Matuschek M, Xie XL, Li SM2010 Aug 720526482