EC number:1.5.1.47
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.5 Acting on the CH-NH group of donors |
| 1.5.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.5.1.47 |
|---|---|
| Description: | Dihydromethanopterin reductase (NAD(P)(+)). |
| Alternative Name: |
H(2)MPT reductase. Dihydromethanopterin reductase. 5,6,7,8-tetrahydromethanopterin 5,6-oxidoreductase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.5.1.47 |
| BRENDA Enzyme Link: | BRENDA 1.5.1.47 |
| KEGG Enzyme Link: | KEGG1.5.1.47 |
| BioCyc Enzyme Link: | BioCyc 1.5.1.47 |
| ExPASy Enzyme Link: | ExPASy1.5.1.47 |
| EC2PDB Enzyme Link: | EC2PDB 1.5.1.47 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.5.1.47 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.5.1.47 |
| IntEnz Enzyme Link: | IntEnz 1.5.1.47 |
| MEDLINE Enzyme Link: | MEDLINE 1.5.1.47 |
| RHEA:35823 | 5,6,7,8-tetrahydromethanopterin + NAD(+) = 7,8-dihydromethanopterin + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[NH;+0:4]-[*:5].[*:6]-[c;H0;+0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[n+;H0:11](-[*:12]):[cH;+0:13]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[N;H0;+0:4]-[*:5].[*:6]-[C;H0;+0:7]1=[CH;+0:13]-[N;H0;+0:11](-[*:12])-[CH;+0:10]=[CH;+0:9]-[CH2;+0:8]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biochemical characterization of a dihydromethanopterin reductase involved in tetrahydromethanopterin biosynthesis in Methylobacterium extorquens AM1. | Caccamo MA, Malone CS, Rasche ME | 2004 Apr | 15028691 |
| RHEA:35819 | 5,6,7,8-tetrahydromethanopterin + NADP(+) = 7,8-dihydromethanopterin + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[NH;+0:4]-[*:5].[*:6]-[c;H0;+0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[n+;H0:11](-[*:12]):[cH;+0:13]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[N;H0;+0:4]-[*:5].[*:6]-[C;H0;+0:7]1=[CH;+0:13]-[N;H0;+0:11](-[*:12])-[CH;+0:10]=[CH;+0:9]-[CH2;+0:8]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biochemical characterization of a dihydromethanopterin reductase involved in tetrahydromethanopterin biosynthesis in Methylobacterium extorquens AM1. | Caccamo MA, Malone CS, Rasche ME | 2004 Apr | 15028691 |