EC number:1.5.1.48
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.5 Acting on the CH-NH group of donors |
| 1.5.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.5.1.48 |
|---|---|
| Description: | 2-methyl-1-pyrroline reductase. |
| Alternative Name: |
(R)-imine reductase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.5.1.48 |
| BRENDA Enzyme Link: | BRENDA 1.5.1.48 |
| KEGG Enzyme Link: | KEGG1.5.1.48 |
| BioCyc Enzyme Link: | BioCyc 1.5.1.48 |
| ExPASy Enzyme Link: | ExPASy1.5.1.48 |
| EC2PDB Enzyme Link: | EC2PDB 1.5.1.48 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.5.1.48 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.5.1.48 |
| IntEnz Enzyme Link: | IntEnz 1.5.1.48 |
| MEDLINE Enzyme Link: | MEDLINE 1.5.1.48 |
| RHEA:41404 | (R)-2-methylpyrrolidine + NADP(+) = 2-methyl-1-pyrroline + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[NH;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[n+;H0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[c;H0;+0:11](-[*:12]):[cH;+0:13]:1>>[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[CH;+0:9]-[CH2;+0:10]-[C;H0;+0:11](-[*:12])=[CH;+0:13]-1.[*:1]-[N;H0;+0:2]=[C;H0;+0:3](-[*:4])-[*:5] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A NADPH-dependent (S)-imine reductase (SIR) from Streptomyces sp. GF3546 for asymmetric synthesis of optically active amines: purification, characterization, gene cloning, and expression. | Mitsukura K, Kuramoto T, Yoshida T, Kimoto N, Yamamoto H, Nagasawa T | 2013 Sep | 23263364 |
| Suppression of graft-versus-host reactivity by a single host-specific blood transfusion to prospective donors of hemopoietic cells. | Knulst AC, Bril-Bazuin C, Savelkoul HF, Benner R | 1991 Sep | 1897027 |