EC number:1.5.1.5

Enzyme

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EC Tree
     1. Oxidoreductases
        1.5 Acting on the CH-NH group of donors
            1.5.1 With NAD+ or NADP+ as acceptor
ID:1.5.1.5
Description:Methylenetetrahydrofolate dehydrogenase (NADP(+)).
Prosite: PDOC00616;
PDB:
PDBScop
6ECR 8056180; 8056181; 8056180; 8056181;
6ECQ 8056180; 8056181; 8056180; 8056181;
6ECP 8056180; 8056181; 8056180; 8056181;
1DIG 8056180; 8056181; 8056180; 8056181;
1DIB 8056180; 8056181; 8056180; 8056181;
 » show all
Cath: 1.10.8.770; 3.30.1510.10; 3.40.50.720; 3.40.50.10280; 3.40.50.10860; 3.40.50.300; 3.10.410.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.5.1.5
BRENDA Enzyme Link: BRENDA 1.5.1.5
KEGG Enzyme Link: KEGG1.5.1.5
BioCyc Enzyme Link: BioCyc 1.5.1.5
ExPASy Enzyme Link: ExPASy1.5.1.5
EC2PDB Enzyme Link: EC2PDB 1.5.1.5
ExplorEnz Enzyme Link: ExplorEnz 1.5.1.5
PRIAM enzyme-specific profiles Link: PRIAM 1.5.1.5
IntEnz Enzyme Link: IntEnz 1.5.1.5
MEDLINE Enzyme Link: MEDLINE 1.5.1.5

EC number:1.5.1.5

MSA:

1.5.1.5;
Phylogenetic Tree:

1.5.1.5;
Uniprot:
M-CSA:
RHEA:22812 (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH
RULE(radius=1) [*:1]-[CH2;+0:2]-[N;H0;+0:3](-[*:4])-[*:5].[*:6]-[n+;H0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[c;H0;+0:11](-[*:12]):[cH;+0:13]:1>>[*:1]-[CH;+0:2]=[N+;H0:3](-[*:4])-[*:5].[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[CH;+0:9]-[CH2;+0:10]-[C;H0;+0:11](-[*:12])=[CH;+0:13]-1
Reaction
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