EC number:1.5.7.1
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.5 Acting on the CH-NH group of donors |
| 1.5.7 With an iron-sulfur protein as acceptor |
| ID: | 1.5.7.1 |
|---|---|
| Description: | Methylenetetrahydrofolate reductase (ferredoxin). |
| Alternative Name: |
5,10-methylenetetrahydrofolate reductase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.5.7.1 |
| BRENDA Enzyme Link: | BRENDA 1.5.7.1 |
| KEGG Enzyme Link: | KEGG1.5.7.1 |
| BioCyc Enzyme Link: | BioCyc 1.5.7.1 |
| ExPASy Enzyme Link: | ExPASy1.5.7.1 |
| EC2PDB Enzyme Link: | EC2PDB 1.5.7.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.5.7.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.5.7.1 |
| IntEnz Enzyme Link: | IntEnz 1.5.7.1 |
| MEDLINE Enzyme Link: | MEDLINE 1.5.7.1 |
| RHEA:14229 | (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 2 oxidized [2Fe-2S]-[ferredoxin] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] |
| RULE(radius=1) | ([*:1]-[CH3;+0:2].[*:3]-[NH;+0:4]-[*:5]).[*:6]-[Fe+;H0:7]-[*:8].[*:9]-[Fe+;H0:10]-[*:11]>>[*:6]-[Fe;H0;+0:7]-[*:8].[*:9]-[Fe;H0;+0:10]-[*:11].[*:3]-[N;H0;+0:4](-[*:5])-[CH2;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and properties of 5,10-methylenetetrahydrofolate reductase, an iron-sulfur flavoprotein from Clostridium formicoaceticum. | Clark JE, Ljungdahl LG | 1984 Sep 10 | 6381490 |