EC number:1.5.98.2
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.5 Acting on the CH-NH group of donors |
| 1.5.98 With other, known, physiological acceptors |
| ID: | 1.5.98.2 |
|---|---|
| Description: | 5,10-methylenetetrahydromethanopterin reductase. |
| Alternative Name: |
N(5),N(10)-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase. N(5),N(10)-methylenetetrahydromethanopterin reductase. Methylene-H(4)MPT reductase. reductase. Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin 5,10-methylenetetrahydromethanopterin cyclohydrolase. |
| Cath: | 3.20.20.30; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.5.98.2 |
| BRENDA Enzyme Link: | BRENDA 1.5.98.2 |
| KEGG Enzyme Link: | KEGG1.5.98.2 |
| BioCyc Enzyme Link: | BioCyc 1.5.98.2 |
| ExPASy Enzyme Link: | ExPASy1.5.98.2 |
| EC2PDB Enzyme Link: | EC2PDB 1.5.98.2 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.5.98.2 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.5.98.2 |
| IntEnz Enzyme Link: | IntEnz 1.5.98.2 |
| MEDLINE Enzyme Link: | MEDLINE 1.5.98.2 |
| RHEA:21144 | 5-methyl-5,6,7,8-tetrahydromethanopterin + H(+) + oxidized coenzyme F420-(gamma-Glu)(n) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420-(gamma-Glu)(n) |
| RULE(radius=1) | ([*:1]-[CH3;+0:2].[*:3]-[NH;+0:4]-[*:5]).[*:6]-[n;H0;+0:7]1:[*:8]:[*:9]:[cH;+0:10]:[c;H0;+0:11](:[*:12])-[c;H0;+0:13]:1:[n;H0;+0:14]:[*:15].[H+;H0:16]>>[*:3]-[N;H0;+0:4](-[*:5])-[CH2;+0:2]-[*:1].[*:6]-[N;H0;+0:7]1-[*:8]:[*:9]-[CH2;+0:10]-[c;H0;+0:11](:[*:12]):[c;H0;+0:13]-1:[nH;+0:14]:[*:15] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and properties of 5,10-methylenetetrahydromethanopterin dehydrogenase and 5,10-methylenetetrahydromethanopterin reductase, two coenzyme F420-dependent enzymes, from Methanosarcina barkeri. | te Brömmelstroet BW, Geerts WJ, Keltjens JT, van der Drift C, Vogels GD | 1991 Sep 20 | 1911853 |
| Si-face stereospecificity at C5 of coenzyme F420 for F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase, F420-dependent N5,N10-methylenetetrahydromethanopterin reductase and F420H2:dimethylnaphthoquinone oxidoreductase. | Kunow J, Schwörer B, Setzke E, Thauer RK | 1993 Jun 15 | 8319675 |
| Purification and properties of N5, N10-methylenetetrahydromethanopterin reductase from Methanobacterium thermoautotrophicum (strain Marburg). | Ma K, Thauer RK | 1990 Jul 20 | 2379499 |
| Purification and properties of 5,10-methylenetetrahydromethanopterin reductase, a coenzyme F420-dependent enzyme, from Methanobacterium thermoautotrophicum strain delta H. | te Brömmelstroet BW, Hensgens CM, Keltjens JT, van der Drift C, Vogels GD | 1990 Feb 5 | 2298726 |
| Purification and properties of 5,10-methenyltetrahydromethanopterin cyclohydrolase from Methanosarcina barkeri. | te Brömmelstroet BW, Hensgens CM, Geerts WJ, Keltjens JT, van der Drift C, Vogels GD | 1990 Feb | 2298699 |
| Purification and properties of N5,N10-methylenetetrahydromethanopterin reductase (coenzyme F420-dependent) from the extreme thermophile Methanopyrus kandleri. | Ma K, Linder D, Stetter KO, Thauer RK | 1991 | 1953299 |