EC number:1.6.5.10
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.6 Acting on NADH or NADPH |
| 1.6.5 With a quinone or similar compound as acceptor |
| ID: | 1.6.5.10 |
|---|---|
| Description: | NADPH dehydrogenase (quinone). |
| Cath: | 3.40.50.360; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.6.5.10 |
| BRENDA Enzyme Link: | BRENDA 1.6.5.10 |
| KEGG Enzyme Link: | KEGG1.6.5.10 |
| BioCyc Enzyme Link: | BioCyc 1.6.5.10 |
| ExPASy Enzyme Link: | ExPASy1.6.5.10 |
| EC2PDB Enzyme Link: | EC2PDB 1.6.5.10 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.6.5.10 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.6.5.10 |
| IntEnz Enzyme Link: | IntEnz 1.6.5.10 |
| MEDLINE Enzyme Link: | MEDLINE 1.6.5.10 |
| RHEA:46164 | a quinone + H(+) + NADPH = a quinol + NADP(+) |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[C;H0;+0:3](-[*:4])-[C;H0;+0:5](=[O;H0;+0:6])-[C;H0;+0:7](-[*:8])=[C;H0;+0:9](-[*:10])-[C;H0;+0:11]-1=[O;H0;+0:12].[*:13]-[N;H0;+0:14]1-[CH;+0:15]=[C;H0;+0:16](-[*:17])-[CH2;+0:18]-[CH;+0:19]=[CH;+0:20]-1.[H+;H0:21]>>[*:1]-[c;H0;+0:2]1:[c;H0;+0:3](-[*:4]):[c;H0;+0:5](-[OH;+0:6]):[c;H0;+0:7](-[*:8]):[c;H0;+0:9](-[*:10]):[c;H0;+0:11]:1-[OH;+0:12].[*:13]-[n+;H0:14]1:[cH;+0:15]:[c;H0;+0:16](-[*:17]):[cH;+0:18]:[cH;+0:19]:[cH;+0:20]:1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of the overproduced NADH dehydrogenase fragment of the NADH:ubiquinone oxidoreductase (complex I) from Escherichia coli. | Braun M, Bungert S, Friedrich T | 1998 Feb 17 | 9485311 |
| The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction. | Li R, Bianchet MA, Talalay P, Amzel LM | 1995 Sep 12 | 7568029 |
| Effects of weight cycling on metabolic control in male outpatients with non-insulin-dependent diabetes mellitus. | Schotte DE, Cohen E, Singh SP | 1990 | 2226388 |
| Characterization and partial purification of microsomal NAD(P)H:quinone oxidoreductases. | Jaiswal AK | 2000 Mar 1 | 10683249 |