Enzyme

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ID:1.6.99.n1
Description:NADPH dehydrogenase (coenzyme F420 dependent).
Alternative Name: NADP reductase (coenzyme F420 dependent).
F420-dependent NADP reductase.

3D structure

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References

RHEA:31363 NADP(+) + reduced coenzyme F420-(gamma-Glu)(n) = 2 H(+) + NADPH + oxidized coenzyme F420-(gamma-Glu)(n)
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[CH2;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10].[*:11]-[c;H0;+0:12]1:[cH;+0:13]:[cH;+0:14]:[cH;+0:15]:[n+;H0:16](-[*:17]):[cH;+0:18]:1>>[*:11]-[C;H0;+0:12]1=[CH;+0:18]-[N;H0;+0:16](-[*:17])-[CH;+0:15]=[CH;+0:14]-[CH2;+0:13]-1.[*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[cH;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10]
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References

TitleAuthorsDatePubMed ID
F420H2:NADP oxidoreductase from Methanobacterium thermoautotrophicum: identification of the encoding gene via functional overexpression in Escherichia coli.Berk H, Thauer RK1998 Oct 309821972
Function of coenzyme F420-dependent NADP reductase in methanogenic archaea containing an NADP-dependent alcohol dehydrogenase.Berk H, Thauer RK1997 Nov9325428
Characterization of an 8-hydroxy-5-deazaflavin:NADPH oxidoreductase from Streptomyces griseus.Eker AP, Hessels JK, Meerwaldt R1989 Jan 272492438