EC number:1.7.1.14
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.7 Acting on other nitrogenous compounds as donors |
| 1.7.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.7.1.14 |
|---|---|
| Description: | Nitric oxide reductase (NAD(P)(+), nitrous oxide-forming). |
| Alternative Name: |
NOR. Fungal nitric oxide reductase. Cytochrome P450nor. |
| Cath: | 1.10.630.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.7.1.14 |
| BRENDA Enzyme Link: | BRENDA 1.7.1.14 |
| KEGG Enzyme Link: | KEGG1.7.1.14 |
| BioCyc Enzyme Link: | BioCyc 1.7.1.14 |
| ExPASy Enzyme Link: | ExPASy1.7.1.14 |
| EC2PDB Enzyme Link: | EC2PDB 1.7.1.14 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.7.1.14 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.7.1.14 |
| IntEnz Enzyme Link: | IntEnz 1.7.1.14 |
| MEDLINE Enzyme Link: | MEDLINE 1.7.1.14 |
| RHEA:29611 | H2O + NADP(+) + nitrous oxide = H(+) + NADPH + 2 nitric oxide |
| RULE(radius=1) | [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[N;H0;+0:9]#[N+;H0:10]-[OH;+0:11].[OH2;+0:12]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[NH;+0:10]=[O;H0;+0:11].[NH;+0:9]=[O;H0;+0:12] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Spectroscopic and kinetic studies on reaction of cytochrome P450nor with nitric oxide. Implication for its nitric oxide reduction mechanism. | Shiro Y, Fujii M, Iizuka T, Adachi S, Tsukamoto K, Nakahara K, Shoun H | 1995 Jan 27 | 7829493 |
| Denitrification by the fungus Fusarium oxysporum and involvement of cytochrome P-450 in the respiratory nitrite reduction. | Shoun H, Tanimoto T | 1991 Jun 15 | 2040619 |
| Structural evidence for direct hydride transfer from NADH to cytochrome P450nor. | Oshima R, Fushinobu S, Su F, Zhang L, Takaya N, Shoun H | 2004 Sep 3 | 15313618 |
| Proton delivery in NO reduction by fungal nitric-oxide reductase. Cryogenic crystallography, spectroscopy, and kinetics of ferric-NO complexes of wild-type and mutant enzymes. | Shimizu H, Obayashi E, Gomi Y, Arakawa H, Park SY, Nakamura H, Adachi S, Shoun H, Shiro Y | 2000 Feb 18 | 10671516 |
| RHEA:29607 | H2O + NAD(+) + nitrous oxide = H(+) + NADH + 2 nitric oxide |
| RULE(radius=1) | [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[N;H0;+0:9]#[N+;H0:10]-[OH;+0:11].[OH2;+0:12]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[NH;+0:10]=[O;H0;+0:11].[NH;+0:9]=[O;H0;+0:12] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Spectroscopic and kinetic studies on reaction of cytochrome P450nor with nitric oxide. Implication for its nitric oxide reduction mechanism. | Shiro Y, Fujii M, Iizuka T, Adachi S, Tsukamoto K, Nakahara K, Shoun H | 1995 Jan 27 | 7829493 |
| Denitrification by the fungus Fusarium oxysporum and involvement of cytochrome P-450 in the respiratory nitrite reduction. | Shoun H, Tanimoto T | 1991 Jun 15 | 2040619 |
| Structural evidence for direct hydride transfer from NADH to cytochrome P450nor. | Oshima R, Fushinobu S, Su F, Zhang L, Takaya N, Shoun H | 2004 Sep 3 | 15313618 |
| Proton delivery in NO reduction by fungal nitric-oxide reductase. Cryogenic crystallography, spectroscopy, and kinetics of ferric-NO complexes of wild-type and mutant enzymes. | Shimizu H, Obayashi E, Gomi Y, Arakawa H, Park SY, Nakamura H, Adachi S, Shoun H, Shiro Y | 2000 Feb 18 | 10671516 |