EC number:1.7.1.17
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.7 Acting on other nitrogenous compounds as donors |
| 1.7.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.7.1.17 |
|---|---|
| Description: | FMN-dependent NADH-azoreductase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.7.1.17 |
| BRENDA Enzyme Link: | BRENDA 1.7.1.17 |
| KEGG Enzyme Link: | KEGG1.7.1.17 |
| BioCyc Enzyme Link: | BioCyc 1.7.1.17 |
| ExPASy Enzyme Link: | ExPASy1.7.1.17 |
| EC2PDB Enzyme Link: | EC2PDB 1.7.1.17 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.7.1.17 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.7.1.17 |
| IntEnz Enzyme Link: | IntEnz 1.7.1.17 |
| MEDLINE Enzyme Link: | MEDLINE 1.7.1.17 |
| RHEA:55872 | anthranilate + N,N-dimethyl-1,4-phenylenediamine + 2 NADP(+) = 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 H(+) + 2 NADPH |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]-[NH2;+0:4].[*:5]-[c;H0;+0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[n+;H0:10](-[*:11]):[cH;+0:12]:1.[*:13]-[n+;H0:14]1:[cH;+0:15]:[cH;+0:16]:[cH;+0:17]:[c;H0;+0:18](-[*:19]):[cH;+0:20]:1>>[*:5]-[C;H0;+0:6]1=[CH;+0:12]-[N;H0;+0:10](-[*:11])-[CH;+0:9]=[CH;+0:8]-[CH2;+0:7]-1.[*:13]-[N;H0;+0:14]1-[CH;+0:15]=[CH;+0:16]-[CH2;+0:17]-[C;H0;+0:18](-[*:19])=[CH;+0:20]-1.[*:1]-[N;H0;+0:2]=[N;H0;+0:4]-[*:3] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characteristics of major Escherichia coli reductases involved in aerobic nitro and azo reduction. | Mercier C, Chalansonnet V, Orenga S, Gilbert C | 2013 Oct | 23795903 |
| Expansion of substrate specificity and catalytic mechanism of azoreductase by X-ray crystallography and site-directed mutagenesis. | Ito K, Nakanishi M, Lee WC, Zhi Y, Sasaki H, Zenno S, Saigo K, Kitade Y, Tanokura M | 2008 May 16 | 18337254 |
| Crystallization and preliminary X-ray analysis of AzoR (azoreductase) from Escherichia coli. | Ito K, Nakanishi M, Lee WC, Sasaki H, Zenno S, Saigo K, Kitade Y, Tanokura M | 2005 Apr 1 | 16511052 |
| Putative ACP phosphodiesterase gene (acpD) encodes an azoreductase. | Nakanishi M, Yatome C, Ishida N, Kitade Y | 2001 Dec 7 | 11583992 |