EC number:1.7.1.2
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.7 Acting on other nitrogenous compounds as donors |
| 1.7.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.7.1.2 | ||
|---|---|---|---|
| Description: | Nitrate reductase (NAD(P)H). | ||
| Alternative Name: |
Nitrate reductase NAD(P)H. (phosphate)). Nitrate reductase (reduced nicotinamide adenine dinucleotide NAD(P)H-nitrate reductase. NAD(P)H bispecific nitrate reductase. Assimilatory nitrate reductase. Assimilatory NAD(P)H-nitrate reductase. | ||
| Prosite: | PDOC00484; PDOC00170; | ||
| PDB: |
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3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.7.1.2 |
| BRENDA Enzyme Link: | BRENDA 1.7.1.2 |
| KEGG Enzyme Link: | KEGG1.7.1.2 |
| BioCyc Enzyme Link: | BioCyc 1.7.1.2 |
| ExPASy Enzyme Link: | ExPASy1.7.1.2 |
| EC2PDB Enzyme Link: | EC2PDB 1.7.1.2 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.7.1.2 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.7.1.2 |
| IntEnz Enzyme Link: | IntEnz 1.7.1.2 |
| MEDLINE Enzyme Link: | MEDLINE 1.7.1.2 |
| RHEA:19061 | H2O + NADP(+) + nitrite = H(+) + NADPH + nitrate |
| RULE(radius=1) | [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[*:9]=[N;H0;+0:10]-[*:11].[OH2;+0:12]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[*:9]=[N+;H0:10](-[*:11])-[OH;+0:12] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Enzymes and associated electron transport systems that catalyse the respiratory reduction of nitrogen oxides and oxyanions. | Berks BC, Ferguson SJ, Moir JW, Richardson DJ | 1995 Dec 12 | 8534676 |
| Structural basis of eukaryotic nitrate reduction: crystal structures of the nitrate reductase active site. | Fischer K, Barbier GG, Hecht HJ, Mendel RR, Campbell WH, Schwarz G | 2005 Apr | 15772287 |
| Structure and function of eukaryotic NAD(P)H:nitrate reductase. | Campbell WH | 2001 Feb | 11289301 |
| RHEA:17913 | H2O + NAD(+) + nitrite = H(+) + NADH + nitrate |
| RULE(radius=1) | [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[*:9]=[N;H0;+0:10]-[*:11].[OH2;+0:12]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[*:9]=[N+;H0:10](-[*:11])-[OH;+0:12] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Differential expression of the arabidopsis nia1 and nia2 genes. cytokinin-induced nitrate reductase activity is correlated with increased nia1 transcription and mrna levels | Yu X, Sukumaran S, Mrton L | 1998 Mar | 9501142 |
| Enzymes and associated electron transport systems that catalyse the respiratory reduction of nitrogen oxides and oxyanions. | Berks BC, Ferguson SJ, Moir JW, Richardson DJ | 1995 Dec 12 | 8534676 |
| Kinetic mechanism of assimilatory NADH:nitrate reductase from Chlorella. | Howard WD, Solomonson LP | 1981 Dec 25 | 6273405 |
| Purification and Kinetics of Higher Plant NADH:Nitrate Reductase. | Campbell WH, Smarrelli J | 1978 Apr | 16660347 |
| Pre-steady-state kinetic analysis of recombinant Arabidopsis NADH:nitrate reductase: rate-limiting processes in catalysis. | Skipper L, Campbell WH, Mertens JA, Lowe DJ | 2001 Jul 20 | 11356830 |
| Structure and function of eukaryotic NAD(P)H:nitrate reductase. | Campbell WH | 2001 Feb | 11289301 |