| EC Tree |
| 1. Oxidoreductases |
| 1.8 Acting on a sulfur group of donors |
| 1.8.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.8.1.18 |
|---|---|
| Description: | NAD(P)H sulfur oxidoreductase (CoA-dependent). |
| Alternative Name: |
S(0) reductase. Coenzyme A-dependent NADPH sulfur oxidoreductase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.8.1.18 |
| BRENDA Enzyme Link: | BRENDA 1.8.1.18 |
| KEGG Enzyme Link: | KEGG1.8.1.18 |
| BioCyc Enzyme Link: | BioCyc 1.8.1.18 |
| ExPASy Enzyme Link: | ExPASy1.8.1.18 |
| EC2PDB Enzyme Link: | EC2PDB 1.8.1.18 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.8.1.18 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.8.1.18 |
| IntEnz Enzyme Link: | IntEnz 1.8.1.18 |
| MEDLINE Enzyme Link: | MEDLINE 1.8.1.18 |
| RHEA:36599 | hydrogen sulfide + NAD(+) = NADH + sulfur |
| RULE(radius=1) | [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[SH2;+0:9]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[S;H0;+0:9] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Deletion strains reveal metabolic roles for key elemental sulfur-responsive proteins in Pyrococcus furiosus. | Bridger SL, Clarkson SM, Stirrett K, DeBarry MB, Lipscomb GL, Schut GJ, Westpheling J, Scott RA, Adams MW | 2011 Dec | 21965560 |
| Insights into the metabolism of elemental sulfur by the hyperthermophilic archaeon Pyrococcus furiosus: characterization of a coenzyme A- dependent NAD(P)H sulfur oxidoreductase. | Schut GJ, Bridger SL, Adams MW | 2007 Jun | 17449625 |
| RHEA:36595 | hydrogen sulfide + NADP(+) = NADPH + sulfur |
| RULE(radius=1) | [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[SH2;+0:9]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[S;H0;+0:9] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Deletion strains reveal metabolic roles for key elemental sulfur-responsive proteins in Pyrococcus furiosus. | Bridger SL, Clarkson SM, Stirrett K, DeBarry MB, Lipscomb GL, Schut GJ, Westpheling J, Scott RA, Adams MW | 2011 Dec | 21965560 |
| Insights into the metabolism of elemental sulfur by the hyperthermophilic archaeon Pyrococcus furiosus: characterization of a coenzyme A- dependent NAD(P)H sulfur oxidoreductase. | Schut GJ, Bridger SL, Adams MW | 2007 Jun | 17449625 |