Enzyme

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EC Tree
     1. Oxidoreductases
        1.8 Acting on a sulfur group of donors
            1.8.1 With NAD+ or NADP+ as acceptor
ID:1.8.1.18
Description:NAD(P)H sulfur oxidoreductase (CoA-dependent).
Alternative Name: S(0) reductase.
Coenzyme A-dependent NADPH sulfur oxidoreductase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.8.1.18
BRENDA Enzyme Link: BRENDA 1.8.1.18
KEGG Enzyme Link: KEGG1.8.1.18
BioCyc Enzyme Link: BioCyc 1.8.1.18
ExPASy Enzyme Link: ExPASy1.8.1.18
EC2PDB Enzyme Link: EC2PDB 1.8.1.18
ExplorEnz Enzyme Link: ExplorEnz 1.8.1.18
PRIAM enzyme-specific profiles Link: PRIAM 1.8.1.18
IntEnz Enzyme Link: IntEnz 1.8.1.18
MEDLINE Enzyme Link: MEDLINE 1.8.1.18
MSA:

1.8.1.18;

Phylogenetic Tree:

1.8.1.18;

Uniprot:
M-CSA:
RHEA:36599 hydrogen sulfide + NAD(+) = NADH + sulfur
RULE(radius=1) [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[SH2;+0:9]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[S;H0;+0:9]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Deletion strains reveal metabolic roles for key elemental sulfur-responsive proteins in Pyrococcus furiosus.Bridger SL, Clarkson SM, Stirrett K, DeBarry MB, Lipscomb GL, Schut GJ, Westpheling J, Scott RA, Adams MW2011 Dec21965560
Insights into the metabolism of elemental sulfur by the hyperthermophilic archaeon Pyrococcus furiosus: characterization of a coenzyme A- dependent NAD(P)H sulfur oxidoreductase.Schut GJ, Bridger SL, Adams MW2007 Jun17449625

RHEA:36595 hydrogen sulfide + NADP(+) = NADPH + sulfur
RULE(radius=1) [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[SH2;+0:9]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[S;H0;+0:9]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Deletion strains reveal metabolic roles for key elemental sulfur-responsive proteins in Pyrococcus furiosus.Bridger SL, Clarkson SM, Stirrett K, DeBarry MB, Lipscomb GL, Schut GJ, Westpheling J, Scott RA, Adams MW2011 Dec21965560
Insights into the metabolism of elemental sulfur by the hyperthermophilic archaeon Pyrococcus furiosus: characterization of a coenzyme A- dependent NAD(P)H sulfur oxidoreductase.Schut GJ, Bridger SL, Adams MW2007 Jun17449625