| EC Tree |
| 1. Oxidoreductases |
| 1.8 Acting on a sulfur group of donors |
| 1.8.98 With other, known, physiological acceptors |
| ID: | 1.8.98.1 |
|---|---|
| Description: | Dihydromethanophenazine:CoB--CoM heterodisulfide reductase. |
| Alternative Name: |
Heterodisulfide reductase. CoB--CoM heterodisulfide reductase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.8.98.1 |
| BRENDA Enzyme Link: | BRENDA 1.8.98.1 |
| KEGG Enzyme Link: | KEGG1.8.98.1 |
| BioCyc Enzyme Link: | BioCyc 1.8.98.1 |
| ExPASy Enzyme Link: | ExPASy1.8.98.1 |
| EC2PDB Enzyme Link: | EC2PDB 1.8.98.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.8.98.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.8.98.1 |
| IntEnz Enzyme Link: | IntEnz 1.8.98.1 |
| MEDLINE Enzyme Link: | MEDLINE 1.8.98.1 |
| RHEA:18085 | coenzyme B + coenzyme M + methanophenazine = coenzyme M-coenzyme B heterodisulfide + dihydromethanophenazine |
| RULE(radius=1) | [*:1]-[SH;+0:2].[*:3]-[SH;+0:4].[*:5]1:[*:6]:[n;H0;+0:7]:[*:8]:[*:9]:[n;H0;+0:10]:1>>[*:1]-[S;H0;+0:2]-[S;H0;+0:4]-[*:3].[*:5]1:[*:6]-[NH;+0:7]-[*:8]:[*:9]-[NH;+0:10]-1 |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and properties of the heme- and iron-sulfur-containing heterodisulfide reductase from Methanosarcina thermophila. | Simianu M, Murakami E, Brewer JM, Ragsdale SW | 1998 Jul 14 | 9665708 |
| Isolation and characterization of methanophenazine and function of phenazines in membrane-bound electron transport of Methanosarcina mazei Gö1. | Abken HJ, Tietze M, Brodersen J, Bäumer S, Beifuss U, Deppenmeier U | 1998 Apr | 9555882 |
| Purification and properties of heterodisulfide reductase from Methanobacterium thermoautotrophicum (strain Marburg). | Hedderich R, Berkessel A, Thauer RK | 1990 Oct 5 | 2121478 |
| Characterization of the intramolecular electron transfer pathway from 2-hydroxyphenazine to the heterodisulfide reductase from Methanosarcina thermophila. | Murakami E, Deppenmeier U, Ragsdale SW | 2001 Jan 26 | 11034998 |