EC number:1.8.98.5
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.8 Acting on a sulfur group of donors |
| 1.8.98 With other, known, physiological acceptors |
| ID: | 1.8.98.5 |
|---|---|
| Description: | H(2):CoB-CoM heterodisulfide,ferredoxin reductase. |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.8.98.5 |
| BRENDA Enzyme Link: | BRENDA 1.8.98.5 |
| KEGG Enzyme Link: | KEGG1.8.98.5 |
| BioCyc Enzyme Link: | BioCyc 1.8.98.5 |
| ExPASy Enzyme Link: | ExPASy1.8.98.5 |
| EC2PDB Enzyme Link: | EC2PDB 1.8.98.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.8.98.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.8.98.5 |
| IntEnz Enzyme Link: | IntEnz 1.8.98.5 |
| MEDLINE Enzyme Link: | MEDLINE 1.8.98.5 |
| RHEA:55748 | coenzyme B + coenzyme M + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H2 + 2 oxidized [2Fe-2S]-[ferredoxin] |
| RULE(radius=1) | [*:1]-[Fe;H0;+0:2]-[*:3].[*:4]-[Fe;H0;+0:5]-[*:6].[*:7]-[SH;+0:8].[*:9]-[SH;+0:10].[H+;H0:11].[H+;H0:12]>>[*:1]-[Fe+;H0:2]-[*:3].[*:4]-[Fe+;H0:5]-[*:6].[*:7]-[S;H0;+0:8]-[S;H0;+0:10]-[*:9].[H;H0;+0:11]-[H;H0;+0:12] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The heterodisulfide reductase from Methanobacterium thermoautotrophicum contains sequence motifs characteristic of pyridine-nucleotide-dependent thioredoxin reductases. | Hedderich R, Koch J, Linder D, Thauer RK | 1994 Oct 1 | 7925445 |
| A hydrogenase-linked gene in Methanobacterium thermoautotrophicum strain delta H encodes a polyferredoxin. | Reeve JN, Beckler GS, Cram DS, Hamilton PT, Brown JW, Krzycki JA, Kolodziej AF, Alex L, Orme-Johnson WH, Walsh CT | 1989 May | 2654933 |
| VhuD facilitates electron flow from H2 or formate to heterodisulfide reductase in Methanococcus maripaludis. | Costa KC, Lie TJ, Xia Q, Leigh JA | 2013 Nov | 24039260 |
| Coupling of ferredoxin and heterodisulfide reduction via electron bifurcation in hydrogenotrophic methanogenic archaea. | Kaster AK, Moll J, Parey K, Thauer RK | 2011 Feb 15 | 21262829 |
| Physiological role of the F420-non-reducing hydrogenase (Mvh) from Methanothermobacter marburgensis. | Stojanowic A, Mander GJ, Duin EC, Hedderich R | 2003 Sep | 12856108 |
| H2: heterodisulfide oxidoreductase complex from Methanobacterium thermoautotrophicum. Composition and properties. | Setzke E, Hedderich R, Heiden S, Thauer RK | 1994 Feb 15 | 8119281 |