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2. Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

ID:	2.1.1.158
Description:	7-methylxanthosine synthase.
Alternative Name:	XRS1. XMT. Xanthosine methyltransferase.
Cath:	1.10.1200.270; 3.40.50.150;

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UniProtKB Enzyme Link:	UniProtKB 2.1.1.158
BRENDA Enzyme Link:	BRENDA 2.1.1.158
KEGG Enzyme Link:	KEGG2.1.1.158
BioCyc Enzyme Link:	BioCyc 2.1.1.158
ExPASy Enzyme Link:	ExPASy2.1.1.158
EC2PDB Enzyme Link:	EC2PDB 2.1.1.158
ExplorEnz Enzyme Link:	ExplorEnz 2.1.1.158
PRIAM enzyme-specific profiles Link:	PRIAM 2.1.1.158
IntEnz Enzyme Link:	IntEnz 2.1.1.158
MEDLINE Enzyme Link:	MEDLINE 2.1.1.158

RHEA:15025	S-adenosyl-L-methionine + xanthosine = 7-methylxanthosine + S-adenosyl-L-homocysteine
RULE(radius=1)	[:1]-[S+;H0:2](-[:3])-[CH3;+0:4].[:5]:[n;H0;+0:6]:[:7]>>[:1]-[S;H0;+0:2]-[:3].[:5]:[n+;H0:6](:[:7])-[CH3;+0:4]
Reaction
Core-to-Core	More

Title	Authors	Date	PubMed ID
The structure of two N-methyltransferases from the caffeine biosynthetic pathway.	McCarthy AA, McCarthy JG	2007 Jun	17434991
Substrate specificity of N-methyltransferase involved in purine alkaloids synthesis is dependent upon one amino acid residue of the enzyme.	Yoneyama N, Morimoto H, Ye CX, Ashihara H, Mizuno K, Kato M	2006 Feb	16333668
The first committed step reaction of caffeine biosynthesis: 7-methylxanthosine synthase is closely homologous to caffeine synthases in coffee (Coffea arabica L.).	Mizuno K, Kato M, Irino F, Yoneyama N, Fujimura T, Ashihara H	2003 Jul 17	12860386
Molecular cloning and functional characterization of three distinct N-methyltransferases involved in the caffeine biosynthetic pathway in coffee plants.	Uefuji H, Ogita S, Yamaguchi Y, Koizumi N, Sano H	2003 May	12746542