EC number:2.1.1.271

Enzyme

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EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.271
Description:Cobalt-precorrin-4 methyltransferase.
Cath: 3.30.950.10; 3.40.1010.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.271
BRENDA Enzyme Link: BRENDA 2.1.1.271
KEGG Enzyme Link: KEGG2.1.1.271
BioCyc Enzyme Link: BioCyc 2.1.1.271
ExPASy Enzyme Link: ExPASy2.1.1.271
EC2PDB Enzyme Link: EC2PDB 2.1.1.271
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.271
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.271
IntEnz Enzyme Link: IntEnz 2.1.1.271
MEDLINE Enzyme Link: MEDLINE 2.1.1.271

EC number:2.1.1.271

MSA:

2.1.1.271;
Phylogenetic Tree:

2.1.1.271;
Uniprot:
M-CSA:
RHEA:26277 Co-precorrin-4 + S-adenosyl-L-methionine = Co-precorrin-5A + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[CH2;+0:2]-[c;H0;+0:3]1:[c;H0;+0:4](-[*:5]):[c;H0;+0:6](-[*:7]):[c;H0;+0:8]2:[n;H0;+0:9]:1-[*:10]-[*:11]-[C;H0;+0:12](-[CH;+0:13](-[*:14])-[*:15])=[CH;+0:16]-2.[*:17]-[S+;H0:18](-[*:19])-[CH3;+0:20]>>[*:1]-[CH;+0:2]=[C;H0;+0:3]1-[C;H0;+0:4](-[*:5])=[C;H0;+0:6](-[*:7])-[C;H0;+0:8]2(-[CH3;+0:20])-[CH2;+0:16]-[C;H0;+0:12](=[C;H0;+0:13](-[*:14])-[*:15])-[*:11]-[*:10]-[N;H0;+0:9]-1-2.[*:17]-[S;H0;+0:18]-[*:19]
Reaction
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References

TitleAuthorsDatePubMed ID
The X-ray structure of a cobalamin biosynthetic enzyme, cobalt-precorrin-4 methyltransferase.Schubert HL, Wilson KS, Raux E, Woodcock SC, Warren MJ1998 Jul9665173
Genetically engineered synthesis and structural characterization of cobalt-precorrin 5A and -5B, two new intermediates on the anaerobic pathway to vitamin B12: definition of the roles of the CbiF and CbiG enzymes.Kajiwara Y, Santander PJ, Roessner CA, Pérez LM, Scott AI2006 Aug 216866557