EC number:2.1.1.286

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.286
Description:25S rRNA (adenine(2142)-N(1))-methyltransferase.
Alternative Name: 25S rRNA m(1)A(2142) methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.286
BRENDA Enzyme Link: BRENDA 2.1.1.286
KEGG Enzyme Link: KEGG2.1.1.286
BioCyc Enzyme Link: BioCyc 2.1.1.286
ExPASy Enzyme Link: ExPASy2.1.1.286
EC2PDB Enzyme Link: EC2PDB 2.1.1.286
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.286
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.286
IntEnz Enzyme Link: IntEnz 2.1.1.286
MEDLINE Enzyme Link: MEDLINE 2.1.1.286

EC number:2.1.1.286

MSA:

2.1.1.286;
Phylogenetic Tree:

2.1.1.286;
Uniprot:
M-CSA:
RHEA:43784 adenosine(2142) in 25S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyladenosine(2142) in 25S rRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[c;H0;+0:6](-[NH2;+0:7]):[n;H0;+0:8]:[*:9]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[c;H0;+0:6](=[NH;+0:7]):[n;H0;+0:8](:[*:9])-[CH3;+0:4]
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References

TitleAuthorsDatePubMed ID
Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae.Sharma S, Watzinger P, Kötter P, Entian KD2013 May 123558746