EC number:2.1.1.287

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.287
Description:25S rRNA (adenine(645)-N(1))-methyltransferase.
Alternative Name: 25S rRNA m(1)A(645) methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.287
BRENDA Enzyme Link: BRENDA 2.1.1.287
KEGG Enzyme Link: KEGG2.1.1.287
BioCyc Enzyme Link: BioCyc 2.1.1.287
ExPASy Enzyme Link: ExPASy2.1.1.287
EC2PDB Enzyme Link: EC2PDB 2.1.1.287
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.287
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.287
IntEnz Enzyme Link: IntEnz 2.1.1.287
MEDLINE Enzyme Link: MEDLINE 2.1.1.287

EC number:2.1.1.287

MSA:

2.1.1.287;
Phylogenetic Tree:

2.1.1.287;
Uniprot:
M-CSA:
RHEA:43792 adenosine(645) in 25S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyladenosine(645) in 25S rRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[c;H0;+0:6](-[NH2;+0:7]):[n;H0;+0:8]:[*:9]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[c;H0;+0:6](=[NH;+0:7]):[n;H0;+0:8](:[*:9])-[CH3;+0:4]
Reaction
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References

TitleAuthorsDatePubMed ID
Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA.Peifer C, Sharma S, Watzinger P, Lamberth S, Kötter P, Entian KD2013 Jan23180764