EC number:2.1.1.33

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.33
Description:tRNA (guanine(46)-N(7))-methyltransferase.
Alternative Name: tRNA guanine 7-methyltransferase.
tRNA (m7G46)-methyltransferase.
tRNA (m(7)G(46)) methyltransferase.
N(7)-methylguanine methylase.
Cath: 3.40.50.150;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.33
BRENDA Enzyme Link: BRENDA 2.1.1.33
KEGG Enzyme Link: KEGG2.1.1.33
BioCyc Enzyme Link: BioCyc 2.1.1.33
ExPASy Enzyme Link: ExPASy2.1.1.33
EC2PDB Enzyme Link: EC2PDB 2.1.1.33
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.33
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.33
IntEnz Enzyme Link: IntEnz 2.1.1.33
MEDLINE Enzyme Link: MEDLINE 2.1.1.33

EC number:2.1.1.33

MSA:

2.1.1.33;
Phylogenetic Tree:

2.1.1.33;
Uniprot:
M-CSA:
RHEA:42708 guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[n;H0;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[n+;H0:6](:[*:7])-[CH3;+0:4]
Reaction
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References

TitleAuthorsDatePubMed ID
7-Methylguanine specific tRNA-methyltransferase from Escherichia coli.Aschhoff HJ, Elten H, Arnold HH, Mahal G, Kersten W, Kersten H1976 Nov794833
Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.Zegers I, Gigot D, van Vliet F, Tricot C, Aymerich S, Bujnicki JM, Kosinski J, Droogmans L200616600901