EC number:2.1.2.10

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.2 Hydroxymethyl-, formyl- and related transferases
ID:2.1.2.10
Description:Aminomethyltransferase.
Alternative Name: Tetrahydrofolate aminomethyltransferase.
Glycine-cleavage system T-protein.
Glycine synthase.
Cath: 1.10.10.10; 1.20.120.530; 3.30.1360.120; 3.30.390.30; 3.30.70.140; 3.30.70.1400; 4.10.820.20; 3.40.640.10; 3.50.50.60; 3.90.1150.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.2.10
BRENDA Enzyme Link: BRENDA 2.1.2.10
KEGG Enzyme Link: KEGG2.1.2.10
BioCyc Enzyme Link: BioCyc 2.1.2.10
ExPASy Enzyme Link: ExPASy2.1.2.10
EC2PDB Enzyme Link: EC2PDB 2.1.2.10
ExplorEnz Enzyme Link: ExplorEnz 2.1.2.10
PRIAM enzyme-specific profiles Link: PRIAM 2.1.2.10
IntEnz Enzyme Link: IntEnz 2.1.2.10
MEDLINE Enzyme Link: MEDLINE 2.1.2.10

EC number:2.1.2.10

MSA:

2.1.2.10;
Phylogenetic Tree:

2.1.2.10;
Uniprot:
M-CSA:
RHEA:16945 (6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)
RULE(radius=1) [*:1]-[NH;+0:2]-[*:3]-[*:4]-[NH;+0:5]-[*:6].[*:7]-[S;H0;+0:8]-[CH2;+0:9]-[NH2;+0:10]>>[*:1]-[N;H0;+0:2]1-[*:3]-[*:4]-[N;H0;+0:5](-[*:6])-[CH2;+0:9]-1.[*:7]-[SH;+0:8].[NH3;+0:10]
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References

TitleAuthorsDatePubMed ID
Purification and characterization of chicken liver T-protein, a component of the glycine cleavage system.Okamura-Ikeda K, Fujiwara K, Motokawa Y1982 Jan 107053363