Enzyme

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EC Tree
     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.219
Description:Demethoxycurcumin synthase.
Cath: 3.40.47.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.219
BRENDA Enzyme Link: BRENDA 2.3.1.219
KEGG Enzyme Link: KEGG2.3.1.219
BioCyc Enzyme Link: BioCyc 2.3.1.219
ExPASy Enzyme Link: ExPASy2.3.1.219
EC2PDB Enzyme Link: EC2PDB 2.3.1.219
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.219
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.219
IntEnz Enzyme Link: IntEnz 2.3.1.219
MEDLINE Enzyme Link: MEDLINE 2.3.1.219
MSA:

2.3.1.219;

Phylogenetic Tree:

2.3.1.219;

Uniprot:
M-CSA:
RHEA:35139 4-coumaroyl-CoA + feruloylacetyl-CoA + H2O = CO2 + 2 CoA + demethoxycurcumin
RULE(radius=1) [*:1]=[C;H0;+0:2](-[*:3])-[S;H0;+0:4]-[*:5].[*:6]=[CH;+0:7]-[C;H0;+0:8](=[*:9])-[S;H0;+0:10]-[*:11].[OH2;+0:12]>>[*:11]-[SH;+0:10].[*:5]-[SH;+0:4].[*:9]=[C;H0;+0:8]=[O;H0;+0:12].[*:6]=[CH;+0:7]-[C;H0;+0:2](=[*:1])-[*:3]
Reaction
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References

TitleAuthorsDatePubMed ID
Identification and characterization of multiple curcumin synthases from the herb Curcuma longa.Katsuyama Y, Kita T, Horinouchi S2009 Sep 319622354

RHEA:35119 (4-coumaroyl)acetyl-CoA + 4-coumaroyl-CoA + H2O = bisdemethoxycurcumin + CO2 + 2 CoA
RULE(radius=1) [*:1]=[C;H0;+0:2](-[*:3])-[S;H0;+0:4]-[*:5].[*:6]=[CH;+0:7]-[C;H0;+0:8](=[*:9])-[S;H0;+0:10]-[*:11].[OH2;+0:12]>>[*:11]-[SH;+0:10].[*:5]-[SH;+0:4].[*:9]=[C;H0;+0:8]=[O;H0;+0:12].[*:6]=[CH;+0:7]-[C;H0;+0:2](=[*:1])-[*:3]
Reaction
Core-to-Core More
Core-to-Core More
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References

TitleAuthorsDatePubMed ID
Identification and characterization of multiple curcumin synthases from the herb Curcuma longa.Katsuyama Y, Kita T, Horinouchi S2009 Sep 319622354