EC number:2.3.1.226
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.226 |
|---|---|
| Description: | Carboxymethylproline synthase. |
| Cath: | 1.20.5.1610; 3.90.226.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.3.1.226 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.226 |
| KEGG Enzyme Link: | KEGG2.3.1.226 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.226 |
| ExPASy Enzyme Link: | ExPASy2.3.1.226 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.226 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.226 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.226 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.226 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.226 |
EC number:2.3.1.226
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:36663 | (S)-1-pyrroline-5-carboxylate + H(+) + H2O + malonyl-CoA = (2S,5S)-5-carboxymethylproline + CO2 + CoA |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]=[CH;+0:3]-[*:4].[*:5]=[C;H0;+0:6](-[OH;+0:7])-[CH2;+0:8]-[C;H0;+0:9](=[*:10])-[S;H0;+0:11]-[*:12].[H+;H0:13].[OH2;+0:14]>>[*:1]-[NH;+0:2]-[CH;+0:3](-[*:4])-[CH2;+0:8]-[C;H0;+0:9](=[*:10])-[OH;+0:14].[*:12]-[SH;+0:11].[*:5]=[C;H0;+0:6]=[O;H0;+0:7] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Carboxymethylproline synthase from Pectobacterium carotorova: a multifaceted member of the crotonase superfamily. | Gerratana B, Arnett SO, Stapon A, Townsend CA | 2004 Dec 21 | 15595850 |
| Carboxymethylproline synthase (CarB), an unusual carbon-carbon bond-forming enzyme of the crotonase superfamily involved in carbapenem biosynthesis. | Sleeman MC, Schofield CJ | 2004 Feb 20 | 14625287 |