EC number:2.3.1.65
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.65 |
|---|---|
| Description: | Bile acid-CoA:amino acid N-acyltransferase. |
| Alternative Name: |
Glycine--taurine N-acyltransferase. Glycine N-choloyltransferase. Cholyl-CoA:taurine N-acyltransferase. Cholyl-CoA glycine-taurine N-acyltransferase. BAT. BACAT. Amino acid N-choloyltransferase. |
| Cath: | 3.30.1050.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.3.1.65 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.65 |
| KEGG Enzyme Link: | KEGG2.3.1.65 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.65 |
| ExPASy Enzyme Link: | ExPASy2.3.1.65 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.65 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.65 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.65 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.65 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.65 |
| RHEA:14001 | choloyl-CoA + glycine = CoA + glycocholate + H(+) |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[S;H0;+0:6]-[*:7]>>[*:7]-[SH;+0:6].[*:3]=[C;H0;+0:4](-[*:5])-[NH;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase. | Falany CN, Johnson MR, Barnes S, Diasio RB | 1994 Jul 29 | 8034703 |
| Rat liver bile acid CoA:amino acid N-acyltransferase: expression, characterization, and peroxisomal localization. | He D, Barnes S, Falany CN | 2003 Dec | 12951368 |
| The human bile acid-CoA:amino acid N-acyltransferase functions in the conjugation of fatty acids to glycine. | O'Byrne J, Hunt MC, Rai DK, Saeki M, Alexson SE | 2003 Sep 5 | 12810727 |
| Molecular cloning and expression of rat liver bile acid CoA ligase. | Falany CN, Xie X, Wheeler JB, Wang J, Smith M, He D, Barnes S | 2002 Dec | 12454267 |