Enzyme

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     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.122
Description:N-acetylgalactosaminide beta-1,3-galactosyltransferase.
Alternative Name: Uridine diphosphogalactose-mucin beta-(1->3)-galactosyltransferase.
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.122
BRENDA Enzyme Link: BRENDA 2.4.1.122
KEGG Enzyme Link: KEGG2.4.1.122
BioCyc Enzyme Link: BioCyc 2.4.1.122
ExPASy Enzyme Link: ExPASy2.4.1.122
EC2PDB Enzyme Link: EC2PDB 2.4.1.122
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.122
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.122
IntEnz Enzyme Link: IntEnz 2.4.1.122
MEDLINE Enzyme Link: MEDLINE 2.4.1.122
MSA:

2.4.1.122;

Phylogenetic Tree:

2.4.1.122;

Uniprot:
M-CSA:
RHEA:15621 an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + H(+) + UDP
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
Purification and properties of UDP-gal:N-acetylgalactosaminide mucin: beta 1,3-galactosyltransferase from swine trachea mucosa.Mendicino J, Sivakami S, Davila M, Chandrasekaran EV1982 Apr 106801057
Identification of the product formed by human erythrocyte galactosyltransferase.Hesford FJ, Berger EG, Van den Eijnden DH1981 Jun 156789880
In vitro bacterial polysaccharide biosynthesis: defining the functions of Wzy and Wzz.Woodward R, Yi W, Li L, Zhao G, Eguchi H, Sridhar PR, Guo H, Song JK, Motari E, Cai L, Kelleher P, Liu X, Han W, Zhang W, Ding Y, Li M, Wang PG2010 Jun20418877
Characterization of a bacterial beta-1,3-galactosyltransferase with application in the synthesis of tumor-associated T-antigen mimics.Yi W, Perali RS, Eguchi H, Motari E, Woodward R, Wang PG2008 Feb 518179256
Cloning and expression of human core 1 beta1,3-galactosyltransferase.Ju T, Brewer K, D'Souza A, Cummings RD, Canfield WM2002 Jan 411677243
Glycosyltransferases involved in elongation of N-glycosidically linked oligosaccharides of the complex or N-acetyllactosamine type.Schachter H, Narasimhan S, Gleeson P, Vella G19836366476