EC number:2.4.1.13
| ID: | 2.4.1.13 |
|---|---|
| Description: | Sucrose synthase. |
| Alternative Name: |
Uridine diphosphoglucose-fructose glucosyltransferase. UDP-glucose-fructose glucosyltransferase. Sucrose-uridine diphosphate glucosyltransferase. Sucrose-UDP glucosyltransferase. Sucrose synthetase. |
| Cath: | 1.20.120.1230; 3.10.450.330; 3.40.50.20; 3.40.50.200; 3.40.50.2000; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.1.13 |
| BRENDA Enzyme Link: | BRENDA 2.4.1.13 |
| KEGG Enzyme Link: | KEGG2.4.1.13 |
| BioCyc Enzyme Link: | BioCyc 2.4.1.13 |
| ExPASy Enzyme Link: | ExPASy2.4.1.13 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.1.13 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.13 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.13 |
| IntEnz Enzyme Link: | IntEnz 2.4.1.13 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.1.13 |
| RHEA:55092 | D-fructose + UDP-alpha-D-glucose = H(+) + sucrose + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants. | Baroja-Fernández E, Muñoz FJ, Saikusa T, Rodríguez-López M, Akazawa T, Pozueta-Romero J | 2003 May | 12773636 |
| Sucrose metabolism in cyanobacteria: sucrose synthase from Anabaena sp. strain PCC 7119 is remarkably different from the plant enzymes with respect to substrate affinity and amino-terminal sequence. | Porchia AC, Curatti L, Salerno GL | 1999 Nov | 10592030 |
| RHEA:55080 | ADP-alpha-D-glucose + D-fructose = ADP + H(+) + sucrose |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The Crystal Structure of Nitrosomonas europaea Sucrose Synthase Reveals Critical Conformational Changes and Insights into Sucrose Metabolism in Prokaryotes. | Wu R, Asención Diez MD, Figueroa CM, Machtey M, Iglesias AA, Ballicora MA, Liu D | 2015 Sep | 26013491 |
| Identification of sucrose synthase in nonphotosynthetic bacteria and characterization of the recombinant enzymes. | Diricks M, De Bruyn F, Van Daele P, Walmagh M, Desmet T | 2015 Oct | 25846332 |
| The unique nucleotide specificity of the sucrose synthase from Thermosynechococcus elongatus. | Figueroa CM, Asención Diez MD, Kuhn ML, McEwen S, Salerno GL, Iglesias AA, Ballicora MA | 2013 Jan 16 | 23196182 |
| Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants. | Baroja-Fernández E, Muñoz FJ, Saikusa T, Rodríguez-López M, Akazawa T, Pozueta-Romero J | 2003 May | 12773636 |
| RHEA:16241 | an NDP-alpha-D-glucose + D-fructose = a ribonucleoside 5'-diphosphate + H(+) + sucrose |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Studies on sucrose synthetase. Kinetic mechanism. | Wolosiuk RA, Pontis HG | 1974 Nov | 4441071 |
| Sucrose synthase activity in the sus1/sus2/sus3/sus4 Arabidopsis mutant is sufficient to support normal cellulose and starch production. | Baroja-Fernández E, Muñoz FJ, Li J, Bahaji A, Almagro G, Montero M, Etxeberria E, Hidalgo M, Sesma MT, Pozueta-Romero J | 2012 Jan 3 | 22184213 |
| Analysis of the sucrose synthase gene family in Arabidopsis. | Bieniawska Z, Paul Barratt DH, Garlick AP, Thole V, Kruger NJ, Martin C, Zrenner R, Smith AM | 2007 Mar | 17257168 |
| Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants. | Baroja-Fernández E, Muñoz FJ, Saikusa T, Rodríguez-López M, Akazawa T, Pozueta-Romero J | 2003 May | 12773636 |
| Purification and characterization of two sucrose synthase isoforms from Japanese pear fruit. | Tanase K, Yamaki S | 2000 Apr | 10845453 |
| Sucrose metabolism in cyanobacteria: sucrose synthase from Anabaena sp. strain PCC 7119 is remarkably different from the plant enzymes with respect to substrate affinity and amino-terminal sequence. | Porchia AC, Curatti L, Salerno GL | 1999 Nov | 10592030 |