EC number:2.4.1.147
| ID: | 2.4.1.147 |
|---|---|
| Description: | acetylglucosaminyltransferase. |
| Alternative Name: |
III. O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase Core 3-beta-GlcNAc-transferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.1.147 |
| BRENDA Enzyme Link: | BRENDA 2.4.1.147 |
| KEGG Enzyme Link: | KEGG2.4.1.147 |
| BioCyc Enzyme Link: | BioCyc 2.4.1.147 |
| ExPASy Enzyme Link: | ExPASy2.4.1.147 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.1.147 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.147 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.147 |
| IntEnz Enzyme Link: | IntEnz 2.4.1.147 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.1.147 |
EC number:2.4.1.147
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:46884 | O(3)-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + O(3)-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mucin synthesis. UDP-GlcNAc:GalNAc-R beta 3-N-acetylglucosaminyltransferase and UDP-GlcNAc:GlcNAc beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 6-N-acetylglucosaminyltransferase from pig and rat colon mucosa. | Brockhausen I, Matta KL, Orr J, Schachter H | 1985 Apr 9 | 3160388 |
| The separation by liquid chromatography (under elevated pressure) of phenyl, benzyl, and O-nitrophenyl glycosides of oligosaccharides. Analysis of substrates and products for four N-acetyl-D-glucosaminyl-transferases involved in mucin synthesis. | Brockhausen I, Rachaman ES, Matta KL, Schachter H | 1983 Aug 16 | 6226356 |
| Synthesis of O-glycan core 3: characterization of UDP-GlcNAc: GalNAc-R beta 3-N-acetyl-glucosaminyltransferase activity from colonic mucosal tissues and lack of the activity in human cancer cell lines. | Vavasseur F, Yang JM, Dole K, Paulsen H, Brockhausen I | 1995 May | 7655172 |
| RHEA:46880 | O(3)-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + O(3)-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mucin synthesis. UDP-GlcNAc:GalNAc-R beta 3-N-acetylglucosaminyltransferase and UDP-GlcNAc:GlcNAc beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 6-N-acetylglucosaminyltransferase from pig and rat colon mucosa. | Brockhausen I, Matta KL, Orr J, Schachter H | 1985 Apr 9 | 3160388 |
| The separation by liquid chromatography (under elevated pressure) of phenyl, benzyl, and O-nitrophenyl glycosides of oligosaccharides. Analysis of substrates and products for four N-acetyl-D-glucosaminyl-transferases involved in mucin synthesis. | Brockhausen I, Rachaman ES, Matta KL, Schachter H | 1983 Aug 16 | 6226356 |
| Synthesis of O-glycan core 3: characterization of UDP-GlcNAc: GalNAc-R beta 3-N-acetyl-glucosaminyltransferase activity from colonic mucosal tissues and lack of the activity in human cancer cell lines. | Vavasseur F, Yang JM, Dole K, Paulsen H, Brockhausen I | 1995 May | 7655172 |